MRPL28 and TSHZ3

Data Source:
BioGRID (two hybrid)

		MRPL28	TSHZ3
Description		mitochondrial ribosomal protein L28	teashirt zinc finger homeobox 3
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Ribosome Mitochondrial Large Ribosomal Subunit Cytosol	Chromatin Nucleus Nucleoplasm Plasma Membrane Growth Cone
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Protein Binding Metal Ion Binding
	Biological Process	Translation Mitochondrial Translational Elongation Mitochondrial Translational Termination	Regulation Of Respiratory Gaseous Exchange By Nervous System Process Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Synaptic Transmission, Glutamatergic Long-term Synaptic Potentiation
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases
GWAS		Body mass index ( 26426971) Heel bone mineral density ( 28869591) Refractive error ( 32231278)	Adventurousness ( 30643258) Chronotype ( 30696823) Cognitive performance ( 19734545) Corneal astigmatism ( 30306274) Diastolic blood pressure ( 27841878) Falling risk ( 32999390) FEV1 ( 30804560) Fractional exhaled nitric oxide (childhood) ( 24315451) General risk tolerance (MTAG) ( 30643258) Lung function (FEV1/FVC) ( 30061609 30804560) Peak expiratory flow ( 30804560) Photic sneeze reflex ( 27182965) Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid) ( 21829377) Post bronchodilator FEV1 in COPD ( 26634245) Refractive error ( 32231278) Systemising ( 31508503) Systolic blood pressure ( 27841878) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		28 interacting genes: ABI2 APP BANP CDCA7L CDR2 ENKD1 FAM9B HMBOX1 HSPB1 HTR2A IKZF3 LARP1B LENG1 LRRK2 NFKBID OXA1L PPL SCNM1 TEF TRAF3IP2 TRAF4 TSHZ3 TSSK3 TUBB3 UPP2 USP2 USP20 ZNF655	30 interacting genes: ANKRA2 APBB1 APEX2 CCHCR1 CEP63 CEP70 COG6 CTBP1 CTBP2 GOLGA2 HSF2BP KASH5 KRT31 KRT40 LRRC73 MAD1L1 MRPL28 MTUS2 PIBF1 RINT1 ROPN1 SPAG5 TAX1BP1 TEPSIN TFIP11 TRAF2 TRIM23 TRIM27 TRIM54 TSC1
Entrez ID		10573	57616
HPRD ID		06889	18351
Ensembl ID		ENSG00000086504	ENSG00000121297
Uniprot IDs		Q13084	Q63HK5
PDB IDs		3J7Y 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG	2DMI
Enriched GO Terms of Interacting Partners?
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