DDX17 and CCDC187

Data Source:
BioGRID (two hybrid)

		DDX17	CCDC187
Description		DEAD-box helicase 17	coiled-coil domain containing 187
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Membrane Nuclear Speck Ribonucleoprotein Complex	Centrosome
	Molecular Function	Transcription Coactivator Activity RNA Binding RNA Helicase Activity Protein Binding ATP Binding RNA-dependent ATPase Activity	Microtubule Binding
	Biological Process	Alternative MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome Epithelial To Mesenchymal Transition Regulation Of Transcription By RNA Polymerase II RRNA Processing RNA Processing MiRNA Metabolic Process Intracellular Estrogen Receptor Signaling Pathway Androgen Receptor Signaling Pathway Gene Silencing By RNA Myoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Defense Response To Virus Regulation Of Skeletal Muscle Cell Differentiation	Microtubule Anchoring
Pathways		SUMOylation of transcription cofactors
Drugs
Diseases
GWAS		Menopause (age at onset) ( 26414677) Resting heart rate ( 27798624) Sleep duration ( 30846698)
Interacting Genes		38 interacting genes: APBB1 APP BYSL CCDC187 CREBBP CSNK2A1 DDX5 DDX6 ESR1 FBL FXR2 GAS8 GRB2 HDAC1 HNRNPH1 HNRNPH3 HNRNPK LNX1 NCOA1 NCOA2 NCOA3 PIN1 PTK6 PTPRD RBM10 RBM14 RBM15 RBM4 RBM5 SF1 SF3B4 SNRNP70 SORBS3 SREK1 SUMO2 WBP11 WBP2 YWHAG	71 interacting genes: ACTN2 ANKRD28 AP2B1 ASB15 BICD2 CARD10 CBY2 CCDC102B CCDC136 CCNDBP1 CDR2 CDR2L CEP63 CEP70 COG6 CRACR2B CSNK2B CYSRT1 DDX17 DEUP1 EFS FRYL FSD2 FXR1 GOLGA2 GOLGA6A GOLGA6L9 GRIPAP1 HMBOX1 HNRNPK HOMER3 HOMEZ HOOK2 HSF2BP IKZF3 INSC KHDRBS3 KIFC3 KRT15 KRT27 KRT31 KRT32 KRTAP6-1 LZTS1 LZTS2 MAGEA6 MCC MDFI MID2 MKRN3 MSS51 MTUS2 NAB2 NCKIPSD PICK1 PLEKHG4 PNMA1 PNMA3 PRKAR1B RINT1 SORBS3 SSX2IP TFIP11 TRAF1 TRAF2 TRIM27 TRIP6 USHBP1 VIM VPS52 ZRANB1
Entrez ID		10521	399693
HPRD ID		10532	14668
Ensembl ID		ENSG00000100201	ENSG00000260220
Uniprot IDs		Q59F66 Q92841	A0A096LP49
PDB IDs		6UV0 6UV1 6UV2 6UV3 6UV4
Enriched GO Terms of Interacting Partners?
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