APPBP2 and CHMP5

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		APPBP2	CHMP5
Description		amyloid beta precursor protein binding protein 2	charged multivesicular body protein 5
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Microtubule Microtubule Associated Complex Cytoplasmic Vesicle Membrane	Nucleus Multivesicular Body Cytosol Endosome Membrane Extracellular Exosome
	Molecular Function	Microtubule Motor Activity Protein Binding	Protein Binding Cadherin Binding
	Biological Process	Intracellular Protein Transport Intracellular Transport	Regulation Of Receptor Recycling Vesicle Budding From Membrane Nucleus Organization Lysosome Organization Mitotic Metaphase Plate Congression Endosome To Lysosome Transport Regulation Of Centrosome Duplication Protein Transport Endosomal Transport Viral Life Cycle Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Midbody Abscission Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly ESCRT III Complex Disassembly
Pathways			Budding and maturation of HIV virion Endosomal Sorting Complex Required For Transport (ESCRT)
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Waist-hip ratio ( 28552196)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Erectile dysfunction and prostate cancer treatment ( 20932654)
Interacting Genes		120 interacting genes: - AADAC ACTN1 AHCY AIM2 AK3 ALDH1L1 ANKRD10 APP AR ARMCX5 ATP13A1 BCL7A BIN2 C1orf50 C6orf226 CALM3 CCDC167 CCDC85C CCNL1 CDK16 CHMP5 CIBAR1 CLCN1 CNTFR COL24A1 CORO2B CREB3 CSNK1G2 CST2 CTC1 CYBA DCD DHRS2 DHX16 DOLK DPEP1 DPYS EID3 ERO1A FAM107A FSTL1 FXYD7 GALNT3 GCSAM GP9 GPRC5C GSTP1 H2AC15 HGFAC HIPK4 HSD3B7 HSPA4 ITGB4 ITGB5 KHK KIF6 KLF11 KLHL35 LANCL2 LONRF3 LUC7L2 LUZP4 MAN2B2 MCOLN1 MFSD3 MGAT4B MLLT3 MMP28 MSH2 MSLN MUL1 MYLK NFYA NPRL3 PCSK5 PI4KAP2 PNPLA5 PPIL6 PPP1R8 PRKAA2 PRKACB PSAP PTCH1 PYROXD2 RAB7B RASSF5 RHEB RILPL1 RNF128 RNF34 RNGTT RRS1 SELENOI SELENOV SLC22A6 SLC25A23 SLC7A10 SLC9A3R1 SNX5 SPDYE2 SPDYE2B ST8SIA5 SYNRG SYT11 TAF11 TAFA4 TBL3 TCF25 TNP2 TRMT2A UBE2R2 UGGT2 WAS WDR24 WFIKKN1 WNT5B ZC3H10 ZCCHC12 ZNF747	16 interacting genes: APPBP2 CHMP1B CHMP4A CHMP4B GTF3A MITD1 NOD2 PDCD10 RPL38 SMARCA4 STAMBP URGCP VPS4B VTA1 ZNF142 ZNF91
Entrez ID		10513	51510
HPRD ID		05616	15408
Ensembl ID		ENSG00000062725	ENSG00000086065
Uniprot IDs		A0A024QZ47 Q92624	Q9NZZ3
PDB IDs			2LXM 3ULY 3UM0 3UM1 3UM2 4TXR
Enriched GO Terms of Interacting Partners?
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