CEBPA and BATF3

Data Source:
BioGRID (fluorescent resonance energy transfer, fluorescent resonance energy transfer)

		CEBPA	BATF3
Description		CCAAT enhancer binding protein alpha	basic leucine zipper ATF-like transcription factor 3
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Nucleolus Intracellular Membrane-bounded Organelle RNA Polymerase II Transcription Regulator Complex	Chromatin Nucleus Nucleoplasm Nucleolus Cytosol
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Kinase Binding Protein Homodimerization Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Urea Cycle Negative Regulation Of Transcription By RNA Polymerase II Liver Development Embryonic Placenta Development Generation Of Precursor Metabolites And Energy Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Mitochondrion Organization Notch Signaling Pathway Cholesterol Metabolic Process Negative Regulation Of Cell Population Proliferation Viral Process Cytokine-mediated Signaling Pathway Myeloid Cell Differentiation Macrophage Differentiation Lung Development Granulocyte Differentiation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Glucose Homeostasis Positive Regulation Of Macrophage Activation Fat Cell Differentiation Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase III Cell Maturation Inner Ear Development Positive Regulation Of Inflammatory Response White Fat Cell Differentiation Brown Fat Cell Differentiation Lipid Homeostasis Interleukin-6-mediated Signaling Pathway Cellular Response To Lithium Ion Cellular Response To Tumor Necrosis Factor Cellular Response To Organic Cyclic Compound	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Response To Virus Myeloid Dendritic Cell Differentiation Dendritic Cell Differentiation
Pathways		Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of granulopoiesis Transcriptional regulation of granulopoiesis
Drugs
Diseases		Acute myeloid leukemia (AML)
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 30013184) Apolipoprotein A1 levels ( 32203549) Asthma ( 31959851 30929738) Asthma (adult onset) ( 31036433 30929738) Asthma (childhood onset) ( 31036433 30929738) Basophil count ( 28031487) Birth weight ( 31043758) Red blood cell count ( 29403010) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500) White blood cell count (basophil) ( 29403010 28158719)	Asthma ( 32296059) Leprosy ( 25642632) Multiple sclerosis ( 31604244) Thiopurine-induced leukopenia in inflammatory bowel disease (conditioned on rs116855232) ( 29923122)
Interacting Genes		58 interacting genes: AR ATF2 ATF3 ATF4 ATF5 BATF BATF2 BATF3 C1QBP CDK2 CDK4 CDKN1A CDKN3 CDX1 CEBPB CEBPD CEBPE CEBPG CREBBP CTNNB1 DBP DDIT3 EDF1 EP300 ESR1 FOS FOSL1 GATA2 GSK3B HNF1A MAPK8 MSX2 MYC NCOA6 NFYA NR3C1 PIAS1 PPP2CA RARA RARB RASGRF1 RB1 RBL1 RFC1 RUNX1 SKP2 SMAD3 SMAD4 SMARCA2 SMARCA4 SOX10 SOX8 SPI1 SRA1 SUMO3 XRCC5 XRCC6 ZBTB16	22 interacting genes: AGXT APPL1 ATF3 ATF4 BACH2 BATF CEBPA CEBPE CEBPG CREB5 CRK DBP DDIT3 EPAS1 FOSL1 GPATCH2L MAFF MAFG NFATC2IP PGR RHOXF2 STAT3
Entrez ID		1050	55509
HPRD ID		00296	18081
Ensembl ID		ENSG00000245848	ENSG00000123685
Uniprot IDs		P49715	Q9NR55
PDB IDs		6DC0
Enriched GO Terms of Interacting Partners?
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