CREB3 and FDPS

Data Source:
BioGRID (two hybrid)

		CREB3	FDPS
Description		cAMP responsive element binding protein 3	farnesyl diphosphate synthase
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Chromatin Nucleus Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Integral Component Of Membrane	Nucleoplasm Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding CAMP Response Element Binding Sequence-specific Double-stranded DNA Binding	RNA Binding Dimethylallyltranstransferase Activity Geranyltranstransferase Activity Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Chemotaxis Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Viral Process Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Monocyte Chemotaxis Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway	Cholesterol Biosynthetic Process Viral Process Geranyl Diphosphate Biosynthetic Process Farnesyl Diphosphate Biosynthetic Process Regulation Of Cholesterol Biosynthetic Process
Pathways		CREB3 factors activate genes CREB3 factors activate genes	Cholesterol biosynthesis Activation of gene expression by SREBF (SREBP)
Drugs			Pamidronic acid Zoledronic acid Alendronic acid Ibandronate Risedronic acid Dimethylallyl Diphosphate Isopentyl Pyrophosphate Geranyl Diphosphate ISOPENTENYL PYROPHOSPHATE Incadronic acid Minodronic acid Farnesyl diphosphate Geranylgeranyl diphosphate
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545)	Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		205 interacting genes: ABHD16A ACKR2 ACSF2 ACSL5 ADTRP AGER AGPAT3 ALG3 ALG8 APH1A APOA2 APOD APPBP2 AQP1 AQP2 AQP4 AQP5 ATF3 ATF4 ATP6AP2 ATP6V0C BCAP29 BCAT2 BCL2L1 BIK BNIP2 BNIP3 BTN2A2 C2 C3orf52 CACFD1 CCR1 CD207 CD82 CDS2 CEBPG CELA3A CES1 CFHR5 CGRRF1 CHMP7 CLCN7 CLDN19 CLDND2 CLP1 CMTM5 CNPY3 CREB3L1 CREB3L3 CT45A5 CTSW CYB561 CYB5B CYBC1 CYBRD1 CYP4F2 DDIT3 DNAJC30 DOLK DRAM1 EBP EMC6 EMD ERG28 FA2H FAM3A FAM3C FDFT1 FDPS FIS1 FMO1 FMO3 FXYD3 FXYD6 GJA1 GJB2 GYPA HCFC1 HDAC3 HMOX1 HVCN1 ICAM4 IGFBP5 ITM2B JUN KCNK1 KLHL30-AS1 KRTCAP2 LAT LHFPL5 LILRB5 LMBR1L LMNA LPCAT2 LTA MAL2 MALL MARCHF5 MFSD11 MFSD5 MGST2 MRPL57 MS4A1 MYADM NAA10 NDUFB6 NEU1 NFE2L2 NFE2L3 NFIL3 NKG7 NRG4 ORMDL1 OS9 P4HA2 PLLP PLN PLP1 PLPP1 PLTP PMP22 PNLIPRP1 PSENEN PTCH1 PTDSS1 PTPN9 RAB23 RABAC1 RHEB RIMS3 RPRM RPS3A RRAS2 RUSF1 SACM1L SAR1B SCAMP4 SCAMP5 SCLY SCP2 SEC22B SEC61G SELENOK SERINC1 SFT2D2 SFTPC SFXN3 SHMT2 SLC19A3 SLC29A1 SLC29A2 SLC29A3 SLC2A3 SLC2A4 SLC30A2 SLC35C2 SLC38A1 SLC39A13 SLC41A2 SLC41A3 SLC49A3 SLC50A1 SLC7A9 SPOCK3 SQLE ST6GAL2 STARD3 STX7 STX8 SYNGR1 SYNPR TAP1 TECR TIMM17B TIMM23B TM4SF4 TMEM100 TMEM115 TMEM140 TMEM14A TMEM14B TMEM14C TMEM19 TMEM203 TMEM222 TMEM230 TMEM234 TMEM243 TMEM51 TMEM54 TRAM1 TRAM1L1 TSPAN2 TSPAN4 TSPAN7 TTLL5 UBE2J1 UNC50 USE1 VKORC1 VTI1B YIPF2 ZDHHC11 ZDHHC21 ZDHHC9	8 interacting genes: ABHD16A ATXN1 CREB3 EIF4ENIF1 FGFR1 RNF19B SLC30A2 SSMEM1
Entrez ID		10488	2224
HPRD ID		07339	00606
Ensembl ID		ENSG00000107175	ENSG00000160752
Uniprot IDs		O43889	A0A087X090 P14324
PDB IDs			1YQ7 1YV5 1ZW5 2F7M 2F89 2F8C 2F8Z 2F92 2F94 2F9K 2OPM 2OPN 2QIS 2RAH 2VF6 3B7L 3CP6 3N1V 3N1W 3N3L 3N45 3N46 3N49 3N5H 3N5J 3N6K 3RYE 3S4J 4DEM 4GA3 4H5C 4H5D 4H5E 4JVJ 4KFA 4KPD 4KPJ 4KQ5 4KQS 4KQU 4L2X 4LFV 4LPG 4LPH 4N1Z 4N9U 4NFI 4NFJ 4NFK 4NG6 4NKE 4NKF 4NUA 4OGU 4P0V 4P0W 4P0X 4PVX 4PVY 4Q23 4QPF 4QXS 4RXA 4XQR 4XQS 4XQT 5CG5 5CG6 5DGM 5DGN 5DGS 5DIQ 5DJP 5DJR 5DJV 5JA0 5JUZ 5JV0 5JV1 5JV2 5KSX 5YGI 6N7Y 6N7Z 6N82 6N83 6OAG 6OAH
Enriched GO Terms of Interacting Partners?
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