CEACAM5 and CEACAM6

Data Source:
BioGRID (pull down)

		CEACAM5	CEACAM6
Description		CEA cell adhesion molecule 5	CEA cell adhesion molecule 6
Image
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Basolateral Plasma Membrane Apical Plasma Membrane Anchored Component Of Membrane Extracellular Exosome Integral Component Of External Side Of Plasma Membrane	Extracellular Space Plasma Membrane Cell Surface Apical Plasma Membrane Anchored Component Of Membrane Azurophil Granule Membrane
	Molecular Function	Protein Binding GPI Anchor Binding Identical Protein Binding Protein Homodimerization Activity	Protein Binding Identical Protein Binding Protein Heterodimerization Activity
	Biological Process	Apoptotic Process Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Negative Regulation Of Myotube Differentiation Homotypic Cell-cell Adhesion Negative Regulation Of Apoptotic Process Leukocyte Migration Negative Regulation Of Anoikis	Apoptotic Process Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Signal Transduction Positive Regulation Of Cell Population Proliferation Positive Regulation Of Cell Migration Positive Regulation Of Heterotypic Cell-cell Adhesion Neutrophil Degranulation Leukocyte Migration Positive Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin Negative Regulation Of Anoikis
Pathways		Post-translational modification: synthesis of GPI-anchored proteins Cell surface interactions at the vascular wall	Fibronectin matrix formation Cell surface interactions at the vascular wall Neutrophil degranulation
Drugs		Labetuzumab S-[(1-Hydroxy-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate
Diseases
GWAS		Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Serum carcinoembryonic antigen levels ( 31666285)	Serum carcinoembryonic antigen levels ( 31666285)
Interacting Genes		6 interacting genes: CEACAM1 CEACAM6 DISP3 EWSR1 HNRNPM UQCC2	32 interacting genes: APP ASPG CARTPT CEACAM1 CEACAM5 CEACAM7 CEACAM8 CIB1 CSTF2 EXOC3L1 FOXH1 GCM2 GPANK1 HGS HPCAL4 KANK2 MSS51 MYOZ1 PITX1 POM121 QRICH1 RHOXF2 SHC3 SMARCD1 TLX3 TNXB UBQLN2 VENTX VEZF1 WWOX ZMYND19 ZNF76
Entrez ID		1048	4680
HPRD ID		00274	01233
Ensembl ID		ENSG00000105388	ENSG00000086548
Uniprot IDs		A0A024R0K5 P06731 Q53G30	P40199
PDB IDs		1E07 2QSQ 2QST 2VER	4WHC 4WTZ 4Y8A 4YIQ
Enriched GO Terms of Interacting Partners?
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