BAIAP2 and SF3A2

Data Source:
BioGRID (two hybrid)

		BAIAP2	SF3A2
Description		BAR/IMD domain containing adaptor protein 2	splicing factor 3a subunit 2
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GO Annotations	Cellular Component	Ruffle Nucleoplasm Cytoplasm Cytosol Plasma Membrane Adherens Junction Actin Cytoskeleton Filopodium Extracellular Exosome	Nucleus Nucleoplasm Spliceosomal Complex U2 SnRNP Nuclear Speck U2-type Prespliceosome U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding Protein C-terminus Binding Cytoskeletal Anchor Activity Identical Protein Binding Proline-rich Region Binding Cadherin Binding Involved In Cell-cell Adhesion	RNA Binding Protein Binding Zinc Ion Binding
	Biological Process	Plasma Membrane Organization Axonogenesis Insulin Receptor Signaling Pathway Regulation Of Cell Shape Response To Bacterium Positive Regulation Of Actin Filament Polymerization Regulation Of Actin Cytoskeleton Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Vascular Endothelial Growth Factor Receptor Signaling Pathway Actin Filament Bundle Assembly Actin Crosslink Formation Cell-cell Adhesion Positive Regulation Of Actin Cytoskeleton Reorganization	Spliceosomal Complex Assembly MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Processing Positive Regulation Of Neuron Projection Development U2-type Prespliceosome Assembly
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis	mRNA Splicing - Major Pathway
Drugs			Copper
Diseases
GWAS		Adult body size ( 32376654) Adverse response to drug ( 30420678) Beef consumption ( 32066663) Body size at age 10 ( 32376654) Breast cancer ( 29871690) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Feeling tense ( 29500382) General factor of neuroticism ( 30867560) Memory performance ( 24392092) Neurociticism ( 29500382) Neuroticism ( 29255261) Serum uric acid levels in response to allopurinol in gout ( 25676789)	Adult body size ( 32376654) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Myocardial infarction ( 24916648) Pulse pressure ( 26390057)
Interacting Genes		39 interacting genes: ADGRB1 APP ATN1 BAIAP2L1 C19orf25 CDC42 COG6 DAPK1 DIAPH1 EGFR ENAH EPS8 ERG28 ESPN GRB10 HOXD8 KANK1 KDM1A LIN7A LIN7B LIN7C MARK2 NCKIPSD NEDD4 PAK1 PBX2 PRR13 RAC1 RTN4 SF3A2 SF3B4 SHANK1 SHANK2 SRPK2 TBX5 TP53BP2 WASF1 WASF2 YWHAG	20 interacting genes: APBB1 ASPH BAIAP2 BEND2 CDC42 GRB2 HTATSF1 LIN54 NCK2 OSTF1 PRPF40A RETN SF3A1 SH3RF1 SMURF2 TCERG1 TFG TRIP10 VEZF1 YY1
Entrez ID		10458	8175
HPRD ID		05686	02877
Ensembl ID		ENSG00000175866	ENSG00000104897
Uniprot IDs		I3L4C2 Q9UQB8	Q05DF2 Q15428
PDB IDs		1WDZ 1Y2O 2YKT 3RNJ 4JS0 6BCR 6BCY 6BD1 6BD2 6BQT 6ZEG 6ZEI	5Z56 5Z57 5Z58 6AH0 6AHD 6FF4 6FF7 6QX9 6Y53 6Y5Q
Enriched GO Terms of Interacting Partners?
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