PPIE and PHYHIP

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PPIE	PHYHIP
Description		peptidylprolyl isomerase E	phytanoyl-CoA 2-hydroxylase interacting protein
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck Secretory Granule Lumen U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome Ficolin-1-rich Granule Lumen	Cytoplasm
	Molecular Function	RNA Binding MRNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Poly(A) Binding Cyclosporin A Binding	Protein Tyrosine Kinase Binding
	Biological Process	MRNA Splicing, Via Spliceosome Protein Peptidyl-prolyl Isomerization Transcription-coupled Nucleotide-excision Repair Regulation Of Transcription, DNA-templated Protein Folding Neutrophil Degranulation Positive Regulation Of Viral Genome Replication	Protein Localization
Pathways		Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER Neutrophil degranulation mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269)	Hypertriglyceridemia ( 23505323)
Interacting Genes		5 interacting genes: KMT2A PHYHIP TRIM55 TRIM63 XAB2	24 interacting genes: ADGRB1 COPS6 DYRK1A EEF1A1 ERG28 FAM131A HDAC11 HNRNPA1 MAGED4B MED8 METTL18 NDRG1 NDUFV3 NFE2 PHYH PNPLA2 PPIE PRMT5 S100A13 SMARCC2 SUPT5H TTR WDR89 ZZEF1
Entrez ID		10450	9796
HPRD ID		03893	16345
Ensembl ID		ENSG00000084072	ENSG00000168490
Uniprot IDs		B3KSZ1 Q9UNP9	Q92561
PDB IDs		1ZMF 2CQB 2KU7 2KYX 2R99 3LPY 3MDF 3UCH 5MQF 5YZG 5Z56 5Z57 6FF7 6ICZ 6ID0 6ID1 7A5P
Enriched GO Terms of Interacting Partners?
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