CDC42EP2 and SEPTIN7

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		CDC42EP2	SEPTIN7
Description		CDC42 effector protein 2	septin 7
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Endomembrane System Microtubule Cytoskeleton Membrane Phagocytic Vesicle	Condensed Chromosome Kinetochore Stress Fiber Nucleus Spindle Cytosol Axoneme Septin Ring Microtubule Cytoskeleton Apical Plasma Membrane Midbody Septin Complex Cell Division Site Cleavage Furrow Extracellular Exosome Sperm Annulus Non-motile Cilium
	Molecular Function	Opioid Peptide Activity GTPase Activator Activity Protein Binding Small GTPase Binding	GTPase Activity Structural Molecule Activity Protein Binding GTP Binding Identical Protein Binding Cadherin Binding Molecular Adaptor Activity
	Biological Process	Actin Filament Organization Rho Protein Signal Transduction Regulation Of Cell Shape Actin Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly Positive Regulation Of Protein-containing Complex Assembly Positive Regulation Of GTPase Activity Cellular Response To Interferon-gamma	Spermatogenesis Regulation Of Embryonic Cell Shape Cell Differentiation Cellular Protein Localization Cilium Assembly Cytoskeleton-dependent Cytokinesis Positive Regulation Of Non-motile Cilium Assembly
Pathways		MAPK6/MAPK4 signaling	MAPK6/MAPK4 signaling
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252)
Interacting Genes		11 interacting genes: ARHGAP26 CASS4 CDC42 COX5B NEDD9 NME7 PICK1 RHOQ SEPTIN6 SEPTIN7 SNCA	13 interacting genes: ANLN CDC42EP2 CDC42EP3 CDC42EP5 CENPE HDAC6 LINC01554 REL S100A4 SEPTIN10 SEPTIN11 SEPTIN5 SEPTIN9
Entrez ID		10435	989
HPRD ID		09363	04398
Ensembl ID		ENSG00000149798	ENSG00000122545
Uniprot IDs		O14613	A0A023T695 A8K3D0 B4DNE4 G3V1Q4 Q16181
PDB IDs			2QAG 3T5D 3TW4 6N0B 6N12 6UQQ
Enriched GO Terms of Interacting Partners?
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