CDR2 and KANSL1

Data Source:
BioGRID (two hybrid)

		CDR2	KANSL1
Description		cerebellar degeneration related protein 2	KAT8 regulatory NSL complex subunit 1
Image		No pdb structure
GO Annotations	Cellular Component		Histone Acetyltransferase Complex Condensed Chromosome Kinetochore Nucleus Nucleoplasm NSL Complex MLL1 Complex
	Molecular Function	Molecular_function Protein Binding	Protein Binding Histone Acetyltransferase Binding
	Biological Process		Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation
Pathways			HATs acetylate histones
Drugs
Diseases
GWAS			Alcohol use disorder (total score) ( 30336701) Alzheimer's disease in APOE e4- carriers ( 25778476) Automobile speeding propensity ( 30643258) Brain morphology (MOSTest) ( 32665545) Breast cancer ( 29059683) Chronotype ( 30696823) Cognitive ability ( 29186694) Cognitive function ( 28093568) Eosinophil counts ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) General factor of neuroticism ( 30867560) Hand grip strength ( 29313844) Handedness (Left-handed vs. non-left-handed) ( 30980028) Handedness (Right-handed vs. non-right-handed) ( 30980028) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Household income ( 31844048) Idiopathic pulmonary fibrosis ( 24429156) Lung function (FEV1) ( 28166213) Lung function (FVC) ( 28166213) Lung function (low FEV1 vs high FEV1) ( 26423011) Lung function in never smokers (low FEV1 vs high FEV1) ( 26423011) Lymphocyte percentage of white cells ( 27863252) Macular thickness ( 30535121) Male-pattern baldness ( 27182965 28196072) Mean corpuscular hemoglobin ( 29403010 32888494 27863252) Mean corpuscular volume ( 29403010 27863252) Mean reticulocyte volume ( 32888494) Monocyte percentage of white cells ( 32888494) Neuroticism ( 29255261) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 32888494 27863252) Oily fish consumption ( 32066663) Osteoarthrosis (time to event) ( 32589924) Parkinson's disease ( 32201043 31660654 28892059) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Plateletcrit ( 32888494) Pork consumption ( 32066663) Pulse pressure ( 27841878) Reaction time ( 29844566) Red blood cell count ( 29403010) Red cell distribution width ( 32888494 28957414) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Risk-taking tendency (4-domain principal component model) ( 30643258) Sum eosinophil basophil counts ( 27863252) Systolic blood pressure ( 27841878) Ventral diencephalon volume ( 31530798) White matter integrity (mean diffusivity) ( 32358547)
Interacting Genes		75 interacting genes: AMOTL2 ANKRD36BP1 AQP1 ARNT2 BEX2 C1orf216 C2CD6 C4orf46 CCDC120 CCDC13 CCDC146 CCDC153 CCDC187 CCDC87 CCHCR1 CDC20 CDR2L CEP57L1 CHIC2 COX5B EIF4E2 ENKD1 FAM110A FAM161A FAM50B FAM90A1 FZR1 GAS8 GEM GMPPA HAUS1 HDAC4 HGS KANSL1 KIF5B KIFC3 LENG1 LIN37 MICALL2 MKKS MNS1 MORF4L2 MRPL28 NDN NTAQ1 OAZ2 PKN1 PRKAA2 PRPF18 PSMA1 RCOR3 RSPH14 RUNX1T1 SCNM1 SH2D4A SMARCD1 SMARCE1 TBC1D22B TCHP TEAD4 TEX28 TMCC2 TRIM23 TRIML2 TSGA10IP TTC23 TTR TXLNA TXLNB UBTFL1 ZGPAT ZMAT2 ZNF250 ZNF35 ZNF417	34 interacting genes: CALCOCO2 CCDC136 CCDC85B CDC5L CDR2 CEP70 DISC1 DTNBP1 EXOC1 FSD2 GOLGA2 HOOK2 HSPB1 KAT8 KDM1A KIFC3 KRT15 MAGEA12 MDFI NECAB2 NINL NUP62 NUTM1 PLEKHA5 PNMA1 PSME3 SMAD3 SPAG5 TFIP11 TRAF2 TRAF4 TRIM27 USHBP1 WDR5
Entrez ID		1039	284058
HPRD ID		06681	11254
Ensembl ID		ENSG00000140743	ENSG00000120071
Uniprot IDs		Q01850	A0A024R9Y2 A0A1W2PRB5 Q7Z3B3
PDB IDs			4CY1 4CY2
Enriched GO Terms of Interacting Partners?
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