KLHL41 and IFRD1

Data Source:
BioGRID (two hybrid)

		KLHL41	IFRD1
Description		kelch like family member 41	interferon related developmental regulator 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ruffle Nucleoplasm Cytoplasm Endoplasmic Reticulum Membrane Cytosol Cytoskeleton Plasma Membrane Pseudopodium M Band Cul3-RING Ubiquitin Ligase Complex Sarcoplasmic Reticulum Membrane	Nucleus
	Molecular Function	Protein Binding
	Biological Process	Striated Muscle Contraction Protein Ubiquitination Myofibril Assembly Regulation Of Lateral Pseudopodium Assembly Skeletal Muscle Cell Differentiation Post-translational Protein Modification Sarcomere Organization Regulation Of Myoblast Differentiation Skeletal Muscle Fiber Development Regulation Of Myoblast Proliferation Regulation Of Skeletal Muscle Cell Differentiation	Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Myoblast Fate Determination
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Amyotrophic lateral sclerosis (age of onset) ( 22959728) Dental caries (decayed, missing and filled teeth) ( 31533690) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Mortality in heart failure ( 20400778) Osteoarthritis (hip) ( 23989986) Refractive error ( 32231278)
Interacting Genes		9 interacting genes: C4orf45 IFRD1 MYBPC1 NRAP POMP RBM4 RCHY1 SLC2A4 TCAP	6 interacting genes: CSNK2A1 HDAC2 HDAC4 KLHL41 MYOD1 RIT1
Entrez ID		10324	3475
HPRD ID		07610	04612
Ensembl ID		ENSG00000239474	ENSG00000006652
Uniprot IDs		O60662	A4D0U1 O00458
PDB IDs
Enriched GO Terms of Interacting Partners?
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