RAMP2 and SLC31A2

Data Source:
BioGRID (pull down)

		RAMP2	SLC31A2
Description		receptor activity modifying protein 2	solute carrier family 31 member 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Plasma Membrane Integral Component Of Plasma Membrane Clathrin-coated Pit Cell Surface Receptor Complex Amylin Receptor Complex 2 Adrenomedullin Receptor Complex	Late Endosome Plasma Membrane Integral Component Of Plasma Membrane Recycling Endosome
	Molecular Function	Adrenomedullin Receptor Activity Protein Binding Coreceptor Activity Amylin Receptor Activity Adrenomedullin Binding	Copper Ion Transmembrane Transporter Activity Protein Binding
	Biological Process	Angiogenesis Vasculogenesis Response To Hypoxia Sprouting Angiogenesis Calcium Ion Transport Intracellular Protein Transport G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Heart Development Female Pregnancy Regulation Of Blood Pressure Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Gene Expression Protein Transport Receptor Internalization Positive Regulation Of Protein Binding Response To Estradiol Response To Progesterone Cellular Response To Hormone Stimulus Adherens Junction Assembly Cellular Response To Vascular Endothelial Growth Factor Stimulus Negative Regulation Of Vascular Permeability Positive Regulation Of Angiogenesis Bicellular Tight Junction Assembly Basement Membrane Assembly Protein Localization To Plasma Membrane Vascular Associated Smooth Muscle Cell Development Amylin Receptor Signaling Pathway Adrenomedullin Receptor Signaling Pathway Negative Regulation Of Endothelial Cell Apoptotic Process Positive Regulation Of Vasculogenesis	Copper Ion Transport Cellular Copper Ion Homeostasis Copper Ion Transmembrane Transport Regulation Of Copper Ion Transmembrane Transport
Pathways		G alpha (s) signalling events Calcitonin-like ligand receptors ADORA2B mediated anti-inflammatory cytokines production
Drugs		Pramlintide
Diseases
GWAS		Pulse pressure ( 30224653)	High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Neutrophil count ( 32888494)
Interacting Genes		7 interacting genes: CALCA CALCRL CIDEB IAPP LCN2 SLC31A2 VIPR1	9 interacting genes: BNIP3 F2RL1 GPR35 HTR2B OPRL1 RAMP1 RAMP2 RAMP3 VKORC1
Entrez ID		10266	1318
HPRD ID		05516	04365
Ensembl ID		ENSG00000131477	ENSG00000136867
Uniprot IDs		A0A024R1Z2 O60895	O15432 Q53X94
PDB IDs		2XVT 3AQE 3AQF 4RWF 6UUN 6V2E
Enriched GO Terms of Interacting Partners?
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