SRRM1 and ABI1

Data Source:
BioGRID (two hybrid)

		SRRM1	ABI1
Description		serine and arginine repetitive matrix 1	abl interactor 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Nuclear Matrix Nuclear Speck Catalytic Step 2 Spliceosome	Intracellular Anatomical Structure Nucleus Endoplasmic Reticulum Cytosol Cytoskeleton Postsynaptic Density Lamellipodium Growth Cone SCAR Complex Filopodium Tip Extracellular Exosome
	Molecular Function	DNA Binding RNA Binding Protein Binding	Protein Binding Cytoskeletal Protein Binding SH3 Domain Binding Protein Tyrosine Kinase Activator Activity Signaling Adaptor Activity Cadherin Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Actin Polymerization Or Depolymerization Negative Regulation Of Cell Population Proliferation Viral Process Peptidyl-tyrosine Phosphorylation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Tyrosine Kinase Activity
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination	Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Adult body size ( 32376654) Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Male-pattern baldness ( 28196072) Systolic blood pressure ( 29208002)
Interacting Genes		13 interacting genes: ABI1 CLK1 CLK2 CSNK2A1 DEK FUS PIN1 SPOP SRPK1 SRPK2 SRRM2 SRRM4 YWHAG	64 interacting genes: ABI2 ABL1 APBB1 C22orf15 CACNA1A CCDC57 CCHCR1 CYFIP2 DST DTNB EIF3H ENAH ENKD1 EPS8 EPS8L1 EVL FAM124B FBXL19 FHL2 GAS7 HHEX HNRNPK HOMER1 HOMER3 HSPA8 KIAA0408 KIAA1217 KTN1 LMO1 MAB21L2 MINK1 MRFAP1 MRFAP1L1 NCK1 NCK2 NCKAP1 NEB NFASC NHSL2 NIN PAK2 PCM1 PRKAA2 PRPF40A RBM15 RCOR3 SMARCD1 SORBS1 SORBS2 SOS1 SOS2 SPTA1 SPTAN1 SRP68 SRRM1 SYNE2 TCERG1 TLN1 TRIP10 TTC23 VARS2 VASP WASF1 WASF2
Entrez ID		10250	10006
HPRD ID		10441	04336
Ensembl ID		ENSG00000133226	ENSG00000136754
Uniprot IDs		A0A0S2Z4W1 B7Z7U0 Q8IYB3	A0A0A0MRT6 B6VEX3 B6VEX4 B6VEX5 Q8IZP0
PDB IDs		1MP1 6FF4 6FF7
Enriched GO Terms of Interacting Partners?
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