DCAF7 and ACE

  • Data Source:
  • BioGRID (affinity chromatography technology)

DCAF7

ACE

Description DDB1 and CUL4 associated factor 7 angiotensin I converting enzyme
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adventurousness ( 30643258)
  • Alzheimer's disease (late onset) ( 24162737 30820047)
  • Angiotensin-converting enzyme activity ( 20066004)
  • Blood metabolite levels ( 24816252)
  • Blood metabolite ratios ( 24816252)
  • Blood protein levels ( 30072576)
  • Cerebrospinal fluid levels of Alzheimer's disease-related proteins ( 25340798)
  • Diastolic blood pressure ( 28135244 27841878 28739976)
  • Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Medication use (calcium channel blockers) ( 31015401)
  • Metabolic traits ( 21886157)
  • Metabolite levels ( 23281178)
  • Serum metabolite levels ( 24625756 23093944)
  • Systolic blood pressure ( 27841878 30578418)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Type 2 diabetes ( 30297969)
Interacting Genes 7 interacting genes: APP ATP13A2 BMPR1B DYRK1B LIG1 PWP2 YWHAG 4 interacting genes: AGTR2 BDKRB2 COMT CSNK2A1
Entrez ID 10238 1636
HPRD ID 09340 00108
Ensembl ID ENSG00000136485 ENSG00000159640
Uniprot IDs P61962 B4DKH4 P12821
PDB IDs 1O86 1O8A 1UZE 1UZF 2C6F 2C6N 2IUL 2IUX 2OC2 2XY9 2XYD 2YDM 3BKK 3BKL 3L3N 3NXQ 4APH 4APJ 4BXK 4BZR 4BZS 4C2N 4C2O 4C2P 4C2Q 4C2R 4CA5 4CA6 4UFA 4UFB 5AM8 5AM9 5AMA 5AMB 5AMC 6EN5 6EN6 6F9R 6F9T 6F9U 6F9V 6H5W 6H5X 6QS1 6TT1 6TT3 6TT4 6ZPQ 6ZPT 6ZPU
Enriched GO Terms of Interacting Partners?
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