CDK3 and NELFA

Data Source:
BioGRID (two hybrid)

		CDK3	NELFA
Description		cyclin dependent kinase 3	negative elongation factor complex member A
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GO Annotations	Cellular Component	Nucleus	Nucleoplasm Cytosol Nuclear Body NELF Complex
	Molecular Function	Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	Protein Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Protein Phosphorylation Cellular Response To DNA Damage Stimulus Cell Population Proliferation G0 To G1 Transition Cell Division Regulation Of Cell Cycle	Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Multicellular Organism Development Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Viral Transcription
Pathways			Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Interacting Genes		39 interacting genes: APP CABLES1 CABLES2 CCNA2 CCNC CCND3 CCNE1 CCNE2 CCNH CCNI CDC37 CDKN1A CDKN1B CDKN3 CKS1B CKS2 E2F1 E2F2 E2F3 FOXP2 FRS2 KIR3DL1 LHX3 LHX4 MEOX2 NEDD4L NELFA OR2G6 OTX2 PAX5 PAX6 PAX8 PPARA RACGAP1 RB1 SPDYE4 STN1 TRIM55 TRIM63	12 interacting genes: APP CDK3 MLH1 NCK2 NELFB NELFCD OPRM1 PIN1 PRR22 SH3KBP1 SIAH1 SMARCD1
Entrez ID		1018	7469
HPRD ID		00446	12080
Ensembl ID		ENSG00000250506	ENSG00000185049
Uniprot IDs		Q00526	A0A0C4DFX9 Q9H3P2
PDB IDs		1LFN	5L3X 6GML
Enriched GO Terms of Interacting Partners?
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