CNIH1 and CYB5R3

Data Source:
BioGRID (two hybrid)

		CNIH1	CYB5R3
Description		cornichon family AMPA receptor auxiliary protein 1	cytochrome b5 reductase 3
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Extracellular Region Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Hemoglobin Complex Membrane Azurophil Granule Lumen Nitric-oxide Synthase Complex
	Molecular Function	Protein Binding	Cytochrome-b5 Reductase Activity, Acting On NAD(P)H Protein Binding AMP Binding ADP Binding Nitrite Reductase (NO-forming) Activity NAD Binding FAD Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Immune Response Signal Transduction COPII Vesicle Coating	Cholesterol Biosynthetic Process Xenobiotic Metabolic Process Nitric Oxide Biosynthetic Process Blood Circulation L-ascorbic Acid Metabolic Process Neutrophil Degranulation
Pathways		COPII-mediated vesicle transport Cargo concentration in the ER	Vitamin C (ascorbate) metabolism Phase I - Functionalization of compounds Neutrophil degranulation
Drugs			NADH Flavin adenine dinucleotide Copper
Diseases			Methemoglobinemia
GWAS		Monobrow thickness ( 26926045)	Initial pursuit acceleration ( 29064472)
Interacting Genes		29 interacting genes: AQP6 BIK CD53 CD79A CLDN7 CPLX4 CYB5R3 ERGIC3 EVI2B FAM209A FCER1G FFAR2 GPR152 GPX8 HTR2C LEUTX LRRC59 MCEMP1 MFF MRM1 OPRM1 RNF24 SHISA4 SLC10A6 SLC18A1 SLC22A23 SLC35C2 SMIM3 TMEM52B	61 interacting genes: ADAM33 AGTRAP AIG1 ALG8 AQP6 ASGR1 BNIP2 CDIPT CERS4 CNIH1 COL8A2 CSGALNACT2 CYB5A CYCS ELOVL4 FAM210B FAM3C FAXDC2 FUNDC2 FXYD3 GAST GPR152 GRM2 HBG2 HSD17B13 LAPTM5 LRCH4 MFSD6 NINJ1 NRM NSG1 NXPE3 ORMDL2 PNLIPRP1 REEP4 SLC10A1 SLC10A6 SLC13A3 SLC22A2 SLC35A4 SLC35B2 SLC38A7 SPP1 STOM TMEM115 TMEM14B TMEM14C TMEM201 TMEM31 TMEM51 TMEM60 TMEM79 TNF TNFRSF10C UBIAD1 VAMP1 VAMP4 VAMP5 VMP1 WFDC2 ZDHHC15
Entrez ID		10175	1727
HPRD ID		16730	08942
Ensembl ID		ENSG00000100528	ENSG00000100243
Uniprot IDs		B2R4P1 O95406	P00387
PDB IDs			1M91 1UMK
Enriched GO Terms of Interacting Partners?
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