ZNF263 and IFT140

Data Source:
BioGRID (genetic interference)

		ZNF263	IFT140
Description		zinc finger protein 263	intraflagellar transport 140
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Photoreceptor Outer Segment Centrosome Centriole Cilium Axoneme Intraciliary Transport Particle A Photoreceptor Connecting Cilium Ciliary Basal Body Ciliary Tip
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Molecular_function Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	Determination Of Left/right Symmetry Heart Development Regulation Of Smoothened Signaling Pathway Neural Tube Patterning Embryonic Camera-type Eye Development Intraciliary Retrograde Transport Intraciliary Transport Involved In Cilium Assembly Photoreceptor Cell Outer Segment Organization Intraciliary Transport Embryonic Digit Morphogenesis Embryonic Cranial Skeleton Morphogenesis Cilium Assembly Protein Localization To Cilium Regulation Of Cilium Assembly Non-motile Cilium Assembly Embryonic Brain Development
Pathways		Generic Transcription Pathway	Hedgehog 'off' state Intraflagellar transport
Drugs
Diseases
GWAS			Coronary artery disease ( 29212778 33020668) Epilepsy and lamotrigine-induced maculopapular eruptions ( 26220383)
Interacting Genes		20 interacting genes: CLK2 CLK3 DVL2 EFEMP2 GPATCH2L JAKMIP2 LNX1 NME7 PCBD1 PLEKHF2 PPL SCAND1 SPG21 SUFU TCAF1 TRIM41 ZNF165 ZNF446 ZSCAN1 ZSCAN22	5 interacting genes: CELSR3 CRK NEK2 PFDN1 RANBP2
Entrez ID		10127	9742
HPRD ID		05008	11093
Ensembl ID		ENSG00000006194	ENSG00000187535
Uniprot IDs		D3DUC1 O14978	Q96RY7
PDB IDs
Enriched GO Terms of Interacting Partners?
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