ZNF263 and ZNF446

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (two hybrid)

		ZNF263	ZNF446
Description		zinc finger protein 263	zinc finger protein 446
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromatin Extracellular Space Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II
Pathways		Generic Transcription Pathway	Generic Transcription Pathway
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661) Uric acid clearance ( 28095793)
Interacting Genes		20 interacting genes: CLK2 CLK3 DVL2 EFEMP2 GPATCH2L JAKMIP2 LNX1 NME7 PCBD1 PLEKHF2 PPL SCAND1 SPG21 SUFU TCAF1 TRIM41 ZNF165 ZNF446 ZSCAN1 ZSCAN22	60 interacting genes: ACTN2 ANKRD1 CCNK COPS2 CYSRT1 DGCR6 DGCR6L EHMT2 EVI5 FHL5 FRMD8 FRS3 GOLGA6L9 INCA1 KIFC3 KRT31 KRT34 KRT35 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP3-1 LNX1 LZTS2 MAGOHB MDFI NBPF19 NOTCH2NLA PGBD1 PIN1 REL SCAND1 SIVA1 SUFU TAX1BP1 TRIM27 UBE2I UBE3A ZKSCAN4 ZKSCAN7 ZNF165 ZNF18 ZNF232 ZNF24 ZNF263 ZNF396 ZNF397 ZNF483 ZNF496 ZSCAN12 ZSCAN16 ZSCAN18 ZSCAN21 ZSCAN22 ZSCAN23 ZSCAN29 ZSCAN30 ZSCAN32 ZSCAN9
Entrez ID		10127	55663
HPRD ID		05008	07934
Ensembl ID		ENSG00000006194	ENSG00000083838
Uniprot IDs		D3DUC1 O14978	Q8NDK2 Q9NWS9 Q9UFF2
PDB IDs
Enriched GO Terms of Interacting Partners?
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