CERT1 and CBS

Data Source:
BioGRID (two hybrid)

		CERT1	CBS
Description		ceramide transporter 1	cystathionine beta-synthase
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GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding Kinase Activity Phosphatidylinositol-4-phosphate Binding Ceramide Binding Ceramide Transfer Activity Ceramide 1-phosphate Binding Ceramide 1-phosphate Transfer Activity	Cystathionine Beta-synthase Activity Protein Binding Oxygen Binding Enzyme Binding Heme Binding Pyridoxal Phosphate Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Protein Homodimerization Activity Metal Ion Binding Nitrite Reductase (NO-forming) Activity Carbon Monoxide Binding Nitric Oxide Binding Modified Amino Acid Binding S-adenosyl-L-methionine Binding
	Biological Process	Cell Morphogenesis In Utero Embryonic Development Heart Morphogenesis Ceramide Metabolic Process Muscle Contraction Immune Response Endoplasmic Reticulum Organization Signal Transduction Cell Population Proliferation Phosphorylation Sphingolipid Biosynthetic Process Response To Endoplasmic Reticulum Stress ER To Golgi Ceramide Transport Ceramide Transport Lipid Homeostasis Mitochondrion Morphogenesis Intermembrane Lipid Transfer Intermembrane Sphingolipid Transfer Ceramide 1-phosphate Transport	Cysteine Biosynthetic Process From Serine L-serine Metabolic Process L-serine Catabolic Process Cysteine Biosynthetic Process Via Cystathionine Cysteine Biosynthetic Process Transsulfuration L-cysteine Catabolic Process DNA Protection Homocysteine Catabolic Process Homocysteine Metabolic Process Hydrogen Sulfide Biosynthetic Process
Pathways			Cysteine formation from homocysteine Cysteine formation from homocysteine Metabolism of ingested SeMet, Sec, MeSec into H2Se
Drugs			Pyridoxal phosphate Ademetionine Serine Cysteine
Diseases			Homocystinuria
GWAS			Blood and toenail selenium levels ( 25343990) Blood metabolite levels ( 24816252) Blood trace element (Se levels) ( 23720494) Homocysteine levels ( 23824729 20031578) Neutrophil count ( 32888494) Obesity-related traits ( 23251661) Plasma homocysteine levels (post-methionine load test) ( 24651765) Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		18 interacting genes: ACTL8 AQP2 ARL6IP1 BSND CBS COL4A3 CSNK1G2 FTSJ1 ITGB3BP MINAR1 PM20D2 POM121 REEP6 RTN3 RTN4 SMU1 STX2 TGM2	23 interacting genes: CBX4 CERT1 DAXX EHHADH FXR2 HGS HID1 HTT NTAQ1 PIAS1 PIAS2 PIAS3 PIN1 PRKAG1 PRKAR1A PSMA1 RANBP9 UBASH3A UBE2I UGP2 VTA1 ZDHHC17 ZMYM5
Entrez ID		10087	875
HPRD ID		05246	01994
Ensembl ID		ENSG00000113163	ENSG00000160200
Uniprot IDs		A0A024RAJ5 A0A2R8Y7C5 Q9Y5P4	B7Z2D6 P0DN79 P35520 Q9NTF0
PDB IDs		2E3M 2E3N 2E3O 2E3P 2E3Q 2E3R 2E3S 2RSG 2Z9Y 2Z9Z 3H3Q 3H3R 3H3S 3H3T 4HHV 5JJD 5ZYG 5ZYH 5ZYI 5ZYJ 5ZYK 5ZYL 5ZYM 6IEZ 6IF0 6J0O 6J81	1JBQ 1M54 4COO 4L0D 4L27 4L28 4L3V 4PCU 4UUU 5MMS
Enriched GO Terms of Interacting Partners?
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