PQBP1 and TXNL4A

Data Source:
HPRD (in vivo, two hybrid)

		PQBP1	TXNL4A
Description		polyglutamine binding protein 1	thioredoxin like 4A
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytoplasmic Stress Granule Nuclear Body Nuclear Speck Neuronal Ribonucleoprotein Granule	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP Cytosol Nuclear Membrane U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome
	Molecular Function	DNA Binding Double-stranded DNA Binding Transcription Coactivator Activity Protein Binding Ribonucleoprotein Complex Binding	Protein Binding
	Biological Process	Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Activation Of Innate Immune Response Positive Regulation Of Defense Response To Virus By Host Regulation Of Transcription, DNA-templated Neuron Projection Development Positive Regulation Of Type I Interferon Production Regulation Of RNA Splicing Innate Immune Response Positive Regulation Of Transcription, DNA-templated Regulation Of Dendrite Morphogenesis Defense Response To Virus Cellular Response To Exogenous DsRNA	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome Cell Cycle Cell Division
Pathways		mRNA Splicing - Major Pathway	mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases		Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS) Non-syndromic X-linked mental retardation
GWAS
Interacting Genes		24 interacting genes: APBB1 APP AQR ATXN1 CLTB EEF1A1 ERG28 ESR1 GOLGA2 HNRNPH2 LNX1 LRIF1 LZTS2 MAPRE1 MED31 POLR2A POU3F2 RAB8A RCVRN SFTPC TLX3 TXNL4A WBP11 WDR77	8 interacting genes: CD2BP2 DDIT4L ERBB3 EXOC5 HNRNPF LZTS2 PQBP1 RHEBL1
Entrez ID		10084	10907
HPRD ID		02354	18252
Ensembl ID		ENSG00000102103	ENSG00000141759
Uniprot IDs		A0A0S2Z4V5 O60828	K7ESL1 P83876
PDB IDs		4BWQ 4BWS 4CDO	1PQN 1QGV 1SYX 3JCR 4BWQ 4BWS 4CDO 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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