DNM1L and MAGEA1

Data Source:
BioGRID (two hybrid)

		DNM1L	MAGEA1
Description		dynamin 1 like	MAGE family member A1
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GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Mitochondrion Mitochondrial Outer Membrane Peroxisome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Microtubule Brush Border Clathrin-coated Pit Membrane Synaptic Vesicle Membrane Mitochondrial Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Presynaptic Endocytic Zone Membrane Mitochondrion-derived Vesicle	Nucleus Cytoplasm Plasma Membrane
	Molecular Function	GTPase Activity GTPase Activator Activity Protein Binding GTP Binding Microtubule Binding Lipid Binding Clathrin Binding GTP-dependent Protein Binding Small GTPase Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding BH2 Domain Binding	Protein Binding Histone Deacetylase Binding
	Biological Process	Mitochondrial Fission Release Of Cytochrome C From Mitochondria Dynamin Family Protein Polymerization Involved In Mitochondrial Fission Calcium Ion Transport Mitochondrion Organization Endoplasmic Reticulum Organization Regulation Of Gene Expression Negative Regulation Of Mitochondrial Fusion Regulation Of Mitochondrion Organization Peroxisome Fission Synaptic Vesicle Recycling Via Endosome Positive Regulation Of Apoptotic Process Positive Regulation Of GTPase Activity Mitochondrial Fragmentation Involved In Apoptotic Process Intracellular Distribution Of Mitochondria Synaptic Vesicle Endocytosis Rhythmic Process Positive Regulation Of Protein Secretion Protein Complex Oligomerization Heart Contraction Positive Regulation Of Dendritic Spine Morphogenesis Membrane Fusion Protein-containing Complex Assembly Necroptotic Process Mitochondrion Morphogenesis Protein Localization To Mitochondrion Positive Regulation Of Neutrophil Chemotaxis Positive Regulation Of Mitochondrial Fission Mitochondrial Membrane Fission Positive Regulation Of Release Of Cytochrome C From Mitochondria Cellular Response To Oxygen-glucose Deprivation Execution Phase Of Apoptosis Regulation Of Peroxisome Organization Positive Regulation Of Synaptic Vesicle Endocytosis Regulation Of Autophagy Of Mitochondrion Regulation Of ATP Metabolic Process Cellular Response To Thapsigargin Regulation Of Ubiquitin Protein Ligase Activity Response To Flavonoid Response To Hypobaric Hypoxia Positive Regulation Of Synaptic Vesicle Exocytosis Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Notch Signaling Pathway
Pathways		Apoptotic execution phase
Drugs
Diseases
GWAS		Mean platelet volume ( 32888494) Platelet count ( 32888494) Platelet distribution width ( 32888494)
Interacting Genes		20 interacting genes: FIS1 FZR1 GSK3B MAGEA1 MAGEA3 MAP3K10 MFF MIEF1 MIEF2 MUL1 PINK1 PRKN RRM2 SCG3 SENP3 SH3GL1 SIRT3 SUMO2 VIM ZBTB24	25 interacting genes: ABI2 CEP57L1 DNM1L HDAC1 HLA-A HLA-B HYPK LRSAM1 MDM4 MIEF1 NOTCH1 PBX3 PCGF6 RAB17 RNF166 S100A9 SELPLG SFN SGK1 SH3GLB2 SHFL SNW1 TRIM31 UQCRB ZNF564
Entrez ID		10059	4100
HPRD ID		04833	02059
Ensembl ID		ENSG00000087470	ENSG00000198681
Uniprot IDs		B4DYR6 O00429	P43355
PDB IDs		3W6N 3W6O 3W6P 4BEJ 4H1U 4H1V 5WP9	1W72 3BO8
Enriched GO Terms of Interacting Partners?
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