FXYD6-FXYD2 and AVPR2

Data Source:
BioGRID (two hybrid)

		FXYD6-FXYD2	AVPR2
Description		FXYD6-FXYD2 readthrough	arginine vasopressin receptor 2
Image		No pdb structure
GO Annotations	Cellular Component		Endosome Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Endocytic Vesicle Clathrin-coated Vesicle Membrane Perinuclear Region Of Cytoplasm
	Molecular Function		G Protein-coupled Receptor Activity Vasopressin Receptor Activity Protein Binding Peptide Binding
	Biological Process		Regulation Of Systemic Arterial Blood Pressure By Vasopressin Renal Water Homeostasis G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Excretion Hemostasis Negative Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Positive Regulation Of Vasoconstriction Membrane Organization
Pathways			Vasopressin-like receptors G alpha (s) signalling events Vasopressin regulates renal water homeostasis via Aquaporins Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis Defective AVP does not bind AVPR2 and causes neurohypophyseal diabetes insipidus (NDI) ADORA2B mediated anti-inflammatory cytokines production
Drugs			Desmopressin Vasopressin Demeclocycline Conivaptan Terlipressin M0002 OPC-51803 Tolvaptan Atosiban Lypressin
Diseases			Congenital nephrogenic diabetes insipidus (NDI)
GWAS		Hippocampal volume in Alzheimer's disease dementia ( 29274321)
Interacting Genes		33 interacting genes: APH1B APOL3 AQP6 AVPR2 BEST1 BNIP3 CERS4 CLDN5 FAM210B GPR152 GPR37L1 GPRC5D MTIF3 PGRMC2 RNF170 SLC10A1 SLC10A6 SLC16A13 SLC19A3 SLC2A13 SLC34A2 SLC35C2 SLC7A8 SPCS1 TLCD4 TMEM14B TMEM167B TMEM205 TMEM41A TMPPE TMX2 TRHR UNC93A	10 interacting genes: ARRB2 AVP C1QTNF1 COMT FXYD6-FXYD2 GNAS GNB1 GNG2 GRK5 SLC41A1
Entrez ID		100533181	554
HPRD ID			02368
Ensembl ID		ENSG00000255245	ENSG00000126895
Uniprot IDs		A0A087WZ82 A0A0A6YYL5	P30518
PDB IDs			4JQI 6NI2 6U1N
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?