LINC02582 and UMOD

Data Source:
BioGRID (unspecified method)

		LINC02582	UMOD
Description		long intergenic non-protein coding RNA 2582	uromodulin
Image		No pdb structure
GO Annotations	Cellular Component		Spindle Pole Extracellular Space Endoplasmic Reticulum Golgi Lumen Cilium Cell Surface Basolateral Plasma Membrane Apical Plasma Membrane Extrinsic Component Of Membrane Anchored Component Of Membrane Ciliary Membrane Extracellular Exosome
	Molecular Function		Extracellular Matrix Structural Constituent Calcium Ion Binding IgG Binding
	Biological Process		Allantoin Metabolic Process Organ Or Tissue Specific Immune Response Renal Water Homeostasis Glomerular Filtration Lipid Metabolic Process Cellular Calcium Ion Homeostasis Cellular Sodium Ion Homeostasis Autophagy Inflammatory Response Cellular Defense Response Endoplasmic Reticulum Organization Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Excretion Negative Regulation Of Cell Population Proliferation RNA Splicing Response To Water Deprivation Peptidyl-threonine Phosphorylation Urate Catabolic Process Ubiquitin-dependent ERAD Pathway Cellular Phosphate Ion Homeostasis Cellular Chloride Ion Homeostasis Response To Lipopolysaccharide Tumor Necrosis Factor-mediated Signaling Pathway Cellular Response To Unfolded Protein Regulation Of Urine Volume Response To Drug Citric Acid Secretion Defense Response To Gram-negative Bacterium Regulation Of Protein Transport Chaperone-mediated Protein Folding Renal Sodium Ion Absorption Collecting Duct Development Juxtaglomerular Apparatus Development Metanephric Ascending Thin Limb Development Metanephric Distal Convoluted Tubule Development Metanephric Thick Ascending Limb Development Protein Localization To Vacuole Apoptotic Signaling Pathway Creatinine Homeostasis Connective Tissue Replacement Neutrophil Migration
Pathways			Asparagine N-linked glycosylation
Drugs
Diseases			Nephronophthisis-medullary cystic kidney disease, including; Nephronophthisis (NPH) ; Nephronophthisis-like nephropathy 1; Medullary cystic kidney disease 1; Medullary cystic kidney disease 2 (MSKD2) Uromodulin-associated kidney diseases, including: Medullary cystic kidney disease 2; Familial juvenile hyperuremic nephropathy; Glomerulocystic kidney disease
GWAS			Chronic kidney disease ( 29124443 26831199 20383146) Chronic kidney disease and serum creatinine levels ( 20686651) Chronic kidney disease x type 2 diabetes interaction ( 32541925) Creatinine levels ( 29124443) Diastolic blood pressure ( 27841878) Diastolic blood pressure x smoking status (ever vs never) interaction (1df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Estimated glomerular filtration rate ( 31015462 29124443 30604766) Femoral neck bone geometry ( 22087292) Glomerular filtration rate ( 27588450) Glomerular filtration rate (creatinine) ( 28452372 26831199) Glomerular filtration rate (cystatin C) ( 28452372) Glomerular filtration rate in diabetes ( 29703844) Glomerular filtration rate in diabetics (creatinine) ( 26831199) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Glomerular filtration rate in type 2 diabetes ( 29703844) Hypertension ( 27618447 21082022) Hyperuricemia ( 29124443) Kidney function decline traits ( 25493955) Kidney stones ( 31729369) Medication use (calcium channel blockers) ( 31015401) Renal function and chronic kidney disease ( 19430482) Renal function-related traits (eGRFcrea) ( 22797727) Renal function-related traits (sCR) ( 22797727) Serum uric acid levels ( 29124443) Urate levels ( 31578528) Urinary uromodulin levels ( 24578125)
Interacting Genes		10 interacting genes: A2M ACTB ALB APOE HBB HPX IGLC6 MAPKAPK3 UMOD USP7	3 interacting genes: LINC02582 LTA MMP8
Entrez ID		100505817	7369
HPRD ID			11771
Ensembl ID		ENSG00000261780	ENSG00000169344
Uniprot IDs			P07911
PDB IDs			4WRN 6TQK 6TQL 6ZS5 6ZYA
Enriched GO Terms of Interacting Partners?
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