TOM1L1 and GLUD2

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TOM1L1	GLUD2
Description		target of myb1 like 1 membrane trafficking protein	glutamate dehydrogenase 2
Image
GO Annotations	Cellular Component	Cytoplasm Lysosome Endosome Golgi Stack Cytosol Endosome Membrane Membrane Extracellular Exosome	Mitochondrion Mitochondrial Matrix Cytosol
	Molecular Function	Protein Binding SH3 Domain Binding Protein Kinase Binding Clathrin Binding Protein Kinase Activator Activity Ubiquitin Binding	Glutamate Dehydrogenase (NAD+) Activity Glutamate Dehydrogenase [NAD(P)+] Activity GTP Binding ADP Binding Leucine Binding
	Biological Process	Intracellular Protein Transport Signal Transduction Positive Regulation Of Protein Autophosphorylation Activation Of Protein Kinase Activity Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Mitotic Nuclear Division Regulation Of DNA Biosynthetic Process	Glutamate Metabolic Process Glutamate Biosynthetic Process Glutamate Catabolic Process
Pathways			Transcriptional activation of mitochondrial biogenesis Glutamate and glutamine metabolism
Drugs			Glutamic acid NADH
Diseases
GWAS		Carotid intima media thickness x smoking interaction ( 32117412) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Photic sneeze reflex ( 27182965) Urinary albumin-to-creatinine ratio ( 32600054)	Fibrinogen levels in ischemic stroke ( 26718567)
Interacting Genes		29 interacting genes: AMFR CCDC47 CELF1 COPS7A CWF19L1 DNAJB13 FYN GLUD2 GRB2 GSN HGS HNRNPH1 MAP3K3 NDC80 NOMO1 PDPN PELP1 PHYH PIK3R1 PWP2 RAB18 TASOR TOLLIP TSG101 TUBA1B UBC UBXN4 VAV2 VCP	1 interacting genes: TOM1L1
Entrez ID		10040	2747
HPRD ID		05266	02143
Ensembl ID		ENSG00000141198	ENSG00000182890
Uniprot IDs		O75674 Q8NI65	A0A140VK14 P49448
PDB IDs		3RRU	6G2U
Enriched GO Terms of Interacting Partners?
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