SRA1 and ALX1

Data Source:
BioGRID (far western blotting)

		SRA1	ALX1
Description		steroid receptor RNA activator 1	ALX homeobox 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Cytosol Plasma Membrane Microtubule Cytoskeleton SCAR Complex Cell Leading Edge Intercellular Bridge Ribonucleoprotein Complex	Chromatin Nucleus Nucleoplasm Golgi Apparatus Nuclear Body
	Molecular Function	Steroid Receptor RNA Activator RNA Binding DNA Binding Transcription Coactivator Activity Protein Binding Nuclear Receptor Coactivator Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Homodimerization Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Apoptotic Process Regulation Of Mitotic Cell Cycle Cell Differentiation Regulation Of Apoptotic Process Negative Regulation Of Myoblast Differentiation Positive Regulation Of Transcription, DNA-templated Cellular Response To Estrogen Stimulus	Negative Regulation Of Transcription By RNA Polymerase II Neural Crest Cell Migration Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis
Pathways
Drugs
Diseases			Frontonasal dysplasia
GWAS		Refractive error ( 32231278) Schizophrenia ( 28991256) Serum immune biomarker levels ( 32066700)	Bone mineral density (Ward's triangle area) ( 27397699) Brain morphology (MOSTest) ( 32665545) Lung function (FEV1) ( 30061609) Lung function (FVC) ( 30061609) Nonsyndromic cleft lip ( 31609978) Nose size ( 27182965)
Interacting Genes		30 interacting genes: ALX1 ATF1 ATF2 ATF3 ATF4 BLZF1 BTG2 CEBPA CREB1 DDIT3 DMTF1 E2F3 EGR1 EGR2 ESR1 ESR2 ESRRG ETS1 ETS2 FOS FOSB FOSL2 GATA1 GTF2B GTF2H2 GTF3C5 HAND1 NR3C1 TFAP2A UBE2Z	17 interacting genes: ALX4 APCS CLIC3 CREBBP EEF1D EP300 GRP IPO13 KAT5 KRTAP4-4 OR52L1 PACRGL RARA RBM45 SRA1 UROC1 ZNF300
Entrez ID		10011	8092
HPRD ID		18716	03316
Ensembl ID		ENSG00000213523	ENSG00000180318
Uniprot IDs		Q9HD15	Q15699 V9HWA7
PDB IDs		2MGX 4NBO
Enriched GO Terms of Interacting Partners?
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