DEPDC5

Description		DEP domain containing 5, GATOR1 subcomplex subunit
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GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Cytosol Cul3-RING Ubiquitin Ligase Complex Perinuclear Region Of Cytoplasm GATOR1 Complex
	Molecular Function	GTPase Activator Activity Protein-containing Complex Binding
	Biological Process	Regulation Of Autophagy Negative Regulation Of TOR Signaling Cellular Response To Amino Acid Starvation Intracellular Signal Transduction Positive Regulation Of GTPase Activity Negative Regulation Of TORC1 Signaling
Pathways		Amino acids regulate mTORC1
Drugs
Diseases
GWAS		Age-related hearing impairment ( 24939585) Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Chronic hepatitis C infection ( 21725309) Fish- and plant-related diet ( 32066663) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Intelligence ( 22449649) Isthmus-cingulate cortex volume ( 31530798) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Type 2 diabetes ( 30130595)
Interacting Genes		10 interacting genes: CCT3 DPPA3 MAD2L1 MAD2L2 MEOX2 MTMR9 RRAGB RRAGC SYT17 USP2
Entrez ID		9681
HPRD ID		16795
Ensembl ID		ENSG00000100150
Uniprot IDs		O75140
PDB IDs		6CES 6CET
Enriched GO Terms of Interacting Partners?
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