GGPS1

Description		geranylgeranyl diphosphate synthase 1
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GO Annotations	Cellular Component	Cytosol
	Molecular Function	Dimethylallyltranstransferase Activity Farnesyltranstransferase Activity Geranyltranstransferase Activity Prenyltransferase Activity Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Cholesterol Biosynthetic Process Isoprenoid Metabolic Process Isoprenoid Biosynthetic Process Geranyl Diphosphate Biosynthetic Process Geranylgeranyl Diphosphate Biosynthetic Process Farnesyl Diphosphate Biosynthetic Process Regulation Of Cholesterol Biosynthetic Process
Pathways		Cholesterol biosynthesis Activation of gene expression by SREBF (SREBP)
Drugs		Pamidronic acid Zoledronic acid Ibandronate Geranyl Diphosphate Farnesyl thiopyrophosphate ISOPENTENYL PYROPHOSPHATE Minodronic acid (1-HYDROXYHEPTANE-1,1-DIYL)BIS(PHOSPHONIC ACID) (1-HYDROXYNONANE-1,1-DIYL)BIS(PHOSPHONIC ACID) (2,2-DIPHOSPHONOETHYL)(DODECYL)DIMETHYLPHOSPHONIUM [2-(3-DIBENZOFURAN-4-YL-PHENYL)-1-HYDROXY-1-PHOSPHONO-ETHYL]-PHOSPHONIC ACID Farnesyl diphosphate Geranylgeranyl diphosphate Lauryl alcohol diphosphonic acid (6E,11E)-HEPTADECA-6,11-DIENE-9,9-DIYLBIS(PHOSPHONIC ACID)
Diseases
GWAS		Asthma ( 29273806)
Novel Interacting Genes		1 novel interacting genes: MX1
Interacting Genes		2 interacting genes: ATOX1 SDCBP
Entrez ID		9453
HPRD ID		06099
Ensembl ID		ENSG00000152904
Uniprot IDs		A0A024R3R2 O95749
PDB IDs		2Q80 6C56 6C57 6G31 6G32 6R4V
Enriched GO Terms of Interacting Partners?
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