SIPA1

Description		signal-induced proliferation-associated 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Membrane Transport Vesicle Protein-containing Complex Perinuclear Region Of Cytoplasm
	Molecular Function	GTPase Activator Activity Protein Binding Protein C-terminus Binding
	Biological Process	Cytoskeleton Organization Negative Regulation Of Cell Adhesion Signal Transduction Negative Regulation Of Cell Growth Intracellular Signal Transduction Cellular Response To Water Deprivation Negative Regulation Of Cell Cycle Regulation Of Small GTPase Mediated Signal Transduction Activation Of GTPase Activity
Pathways		Rap1 signalling
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Asthma ( 31619474) Coronary artery disease ( 33020668) Diastolic blood pressure ( 27841878) Diastolic blood pressure (cigarette smoking interaction) ( 29455858) Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) HDL cholesterol ( 30275531) Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Metabolic syndrome ( 31589552) Platelet count ( 27863252) Pulse pressure ( 30578418) Red cell distribution width ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systolic blood pressure ( 27841878 27618452 30578418) Systolic blood pressure (cigarette smoking interaction) ( 29455858) Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes		3 interacting genes: CDKN1A COP1 DVL1
Entrez ID		6494
HPRD ID		03713
Ensembl ID		ENSG00000213445
Uniprot IDs		Q96FS4
PDB IDs
Enriched GO Terms of Interacting Partners?
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