TM6SF2

Description		transmembrane 6 superfamily member 2
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Molecular_function Protein Binding Identical Protein Binding
	Biological Process	Lipid Metabolic Process Regulation Of Lipid Metabolic Process Lipid Homeostasis
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Bipolar II disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Cirrhosis (alcohol related) ( 26482880) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Liver fat content (MRI proton density fat fraction measure) ( 32247823) Liver fibrosis and steatohepatitis severity (MRI cT1 measure) ( 32247823) Low density lipoprotein cholesterol levels ( 32154731) Medication use (HMG CoA reductase inhibitors) ( 31015401) Nonalcoholic fatty liver disease ( 24531328 29385134) Nonalcoholic steatohepatitis ( 32298765) Schizophrenia ( 25056061 29483656 23974872) Triglyceride levels ( 32203549 32154731 29403010) Type 2 diabetes ( 30297969 29632382) Type 2 diabetes (adjusted for BMI) ( 29632382) Vitamin levels ( 23696881)
Interacting Genes		10 interacting genes: ARL13B BCL2L13 FAM209A HIBADH KCNJ6 MUC1 PVR SCN3B SSMEM1 TMEM237
Entrez ID		53345
HPRD ID		12109
Ensembl ID		ENSG00000213996
Uniprot IDs		Q8N8A7 Q9BZW4
PDB IDs
Enriched GO Terms of Interacting Partners?
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