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RTCB

Description RNA 2',3'-cyclic phosphate and 5'-OH ligase
Image No pdb structure
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Cytoplasm
  • Cytosol
  • Intracellular Membrane-bounded Organelle
  • TRNA-splicing Ligase Complex
Molecular Function
  • RNA Binding
  • RNA Ligase (ATP) Activity
  • Protein Binding
  • GTP Binding
  • Vinculin Binding
  • Metal Ion Binding
Biological Process
  • TRNA Exon Ligation Utilizing 2',3' Cyclic Phosphate Of 5'-exon As Source Of Linkage Phosphate
  • TRNA Splicing, Via Endonucleolytic Cleavage And Ligation
Pathways
  • tRNA processing in the nucleus
Drugs
  • Sucrose
Diseases
GWAS
  • Dimensional psychopathology (Arousal) ( 29496196)
  • Dimensional psychopathology (Negative) ( 29496196)
Interacting Genes 75 interacting genes: CRK ESR1 LINC01554 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I
Entrez ID 51493
HPRD ID 13695
Ensembl ID ENSG00000100220
Uniprot IDs Q9Y3I0
PDB IDs
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025