IL5RA

Description		interleukin 5 receptor subunit alpha
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GO Annotations	Cellular Component	Extracellular Space Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Receptor Complex
	Molecular Function	Cytokine Receptor Activity Interleukin-5 Receptor Activity Protein Binding Cytokine Binding
	Biological Process	MAPK Cascade Inflammatory Response To Antigenic Stimulus Signal Transduction Cytokine-mediated Signaling Pathway Regulation Of Interleukin-5 Production Interleukin-5-mediated Signaling Pathway Positive Regulation Of Leukocyte Proliferation
Pathways		Interleukin-3, Interleukin-5 and GM-CSF signaling RAF/MAP kinase cascade Interleukin receptor SHC signaling
Drugs		Benralizumab
Diseases
GWAS		Asthma (childhood onset) ( 22560479) Basophil count ( 32888494) Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 32888494 27863252) Blood protein levels ( 30072576 29875488 28240269) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Immune response to smallpox vaccine (IL-6) ( 22542470) Metabolite levels ( 23823483) Neutrophil percentage of granulocytes ( 27863252) Oleic acid (18:1n-9) levels ( 23362303) Sum eosinophil basophil counts ( 27863252) White blood cell count (basophil) ( 27863252)
Interacting Genes		7 interacting genes: CSF2RB EGFR IL5 JAK1 JAK2 SDCBP UNC119
Entrez ID		3568
HPRD ID		00998
Ensembl ID		ENSG00000091181
Uniprot IDs		A0A024R2E8 Q01344 Q8NHV7
PDB IDs		1OBX 1OBZ 3QT2 3VA2 6H41
Enriched GO Terms of Interacting Partners?
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