PARVB

Description		parvin beta
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Focal Adhesion Actin Cytoskeleton Z Disc Lamellipodium
	Molecular Function	Actin Binding Protein Binding
	Biological Process	Establishment Or Maintenance Of Cell Polarity Cell Projection Assembly Lamellipodium Assembly Actin Cytoskeleton Reorganization Substrate Adhesion-dependent Cell Spreading Establishment Or Maintenance Of Cell Polarity Regulating Cell Shape
Pathways		Cell-extracellular matrix interactions Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Hematological and biochemical traits ( 20139978) Lewy body disease ( 25188341) Nonalcoholic fatty liver disease ( 22719876) Pediatric non-alcoholic fatty liver disease activity score ( 23535911) Response to chemotherapy in breast cancer (hypertension) (bevacizumab) ( 25117820) Response to chemotherapy in breast cancer hypertensive cases (cumulative dose) (bevacizumab) ( 25117820) Systemic sclerosis (anti-centromere-positive) ( 29293537)
Interacting Genes		2 interacting genes: ARHGEF6 ILK
Entrez ID		29780
HPRD ID		16284
Ensembl ID		ENSG00000188677
Uniprot IDs		A0A087WZB5 Q9HBI1
PDB IDs		4EDL 4EDM 4EDN
Enriched GO Terms of Interacting Partners?
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