GPI

Description		glucose-6-phosphate isomerase
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GO Annotations	Cellular Component	Extracellular Region Nucleoplasm Cytosol Plasma Membrane Membrane Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Glucose-6-phosphate Isomerase Activity Cytokine Activity Protein Binding Growth Factor Activity Ubiquitin Protein Ligase Binding Monosaccharide Binding
	Biological Process	Positive Regulation Of Immunoglobulin Production Carbohydrate Metabolic Process Gluconeogenesis Glycolytic Process Humoral Immune Response Signal Transduction Hemostasis Positive Regulation Of Endothelial Cell Migration Neutrophil Degranulation Glucose 6-phosphate Metabolic Process Canonical Glycolysis
Pathways		TP53 Regulates Metabolic Genes Neutrophil degranulation Glycolysis Gluconeogenesis
Drugs		alpha-D-glucose 6-phosphate 6-phospho-D-gluconic acid 5-phospho-D-arabinohydroxamic acid D-glucitol 6-phosphate 5-Phosphoarabinonic Acid Glucose-6-Phosphate D-erythrose 4-phosphate Fructose-6-phosphate Copper Artenimol
Diseases		Anemia due to disorders of glycolytic enzymes, including: Hexokinase (HK) deficiency; Phosphoglycerate kinase 1 (PGK1) deficiency; Triose-phosphate isomerase (TPI) deficiency; Glucose phosphate isomerase (GPI) deficiency; Bisphosphoglycerate mutase (BPGM) deficiency
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Mean corpuscular volume ( 32888494)
Novel Interacting Genes		1 novel interacting genes: DCC
Interacting Genes		6 interacting genes: AMFR CSNK2A1 IGFBP3 LINC01554 PARP14 PCNA
Entrez ID		2821
HPRD ID		01394
Ensembl ID		ENSG00000105220
Uniprot IDs		A0A2U3TZU2 B4DE36 P06744
PDB IDs		1IAT 1IRI 1JIQ 1JLH 1NUH 6XUH 6XUI
Enriched GO Terms of Interacting Partners?
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