ABCA2

Description		ATP binding cassette subfamily A member 2
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Microtubule Organizing Center Plasma Membrane Endosome Membrane Membrane Integral Component Of Membrane Cytoplasmic Vesicle ATP-binding Cassette (ABC) Transporter Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Nucleotide Binding Lipid Transporter Activity ATP Binding ATPase Activity ATPase-coupled Transmembrane Transporter Activity Endopeptidase Regulator Activity Ceramide Floppase Activity
	Biological Process	Ganglioside Metabolic Process Regulation Of Transcription By RNA Polymerase II Lipid Metabolic Process Sphingomyelin Metabolic Process Glycosphingolipid Metabolic Process Lipid Transport Locomotory Behavior Regulation Of Cholesterol Esterification Central Nervous System Myelin Formation Regulation Of Intracellular Cholesterol Transport Negative Regulation Of Intracellular Cholesterol Transport Positive Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Response To Drug Cholesterol Homeostasis Positive Regulation Of Amyloid Precursor Protein Biosynthetic Process Regulation Of Cholesterol Biosynthetic Process Sphingosine Biosynthetic Process Response To Steroid Hormone Regulation Of Endopeptidase Activity Transmembrane Transport Regulation Of Protein Glycosylation Response To Cholesterol Negative Regulation Of Phospholipid Biosynthetic Process Negative Regulation Of Sphingolipid Biosynthetic Process Cellular Sphingolipid Homeostasis Negative Regulation Of Cholesterol Efflux Ceramide Translocation Transport Across Blood-brain Barrier Negative Regulation Of Cholesterol Esterification Regulation Of Post-translational Protein Modification Positive Regulation Of Amyloid-beta Formation Positive Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Protein Localization To Cell Periphery Negative Regulation Of Low-density Lipoprotein Receptor Activity Negative Regulation Of Receptor-mediated Endocytosis Involved In Cholesterol Transport Regulation Of Protein Localization To Cell Surface
Pathways		ABC transporters in lipid homeostasis
Drugs
Diseases
GWAS		Adverse response to drug ( 30420678) White blood cell count ( 32888494)
Interacting Genes		4 interacting genes: CACNA1A CDK5RAP2 DRD2 HTR6
Entrez ID		20
HPRD ID		08967
Ensembl ID		ENSG00000107331
Uniprot IDs		Q9BZC7
PDB IDs
Enriched GO Terms of Interacting Partners?
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