CHRNB4

Description cholinergic receptor nicotinic beta 4 subunit
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Attention function in attention deficit hyperactive disorder ( 26174813)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Benign childhood epilepsy with centro-temporal spikes ( 32580138)
  • BMI (smoking interaction) ( 28443625)
  • BMI in smokers ( 28443625)
  • Body mass index (joint analysis main effects and smoking interaction) ( 28443625)
  • Chronic obstructive pulmonary disease ( 30804561)
  • Coronary artery disease ( 32469254 33020668)
  • Diffusing capacity of carbon monoxide ( 30694715)
  • Exhaled carbon monoxide levels ( 25072098)
  • Gut microbiota relative abundance (Parabacteroides) ( 33208821)
  • Lung adenocarcinoma ( 28604730)
  • Lung cancer ( 28604730 18385738 18780872)
  • Lung cancer in ever smokers ( 28604730)
  • Nicotine dependence ( 18385739 26440539)
  • Post bronchodilator FEV1 ( 26634245)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
  • Refractive error ( 32231278)
  • Schizophrenia ( 25056061 29483656)
  • Small cell lung carcinoma ( 28604730)
  • Smoking status (heavy vs light) ( 28520984)
  • Squamous cell lung carcinoma ( 28604730)
  • Sudden cardiac arrest ( 21658281)
Novel Interacting Genes 2 novel interacting genes: LARP7 SLC2A1
Interacting Genes 6 interacting genes: CHRNA2 CHRNA3 CHRNA4 CHRNA5 MEOX2 UBQLN1
Entrez ID 1143
HPRD ID 00337
Ensembl ID ENSG00000117971
Uniprot IDs P30926
PDB IDs 2ASG 6PV7 6PV8
Enriched GO Terms of Interacting Partners?
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