CASP8AP2 and CREM

  • Number of citations of the paper that reports this interaction (PubMedID 21988832)
  • 87
  • Data Source:
  • BioGRID (two hybrid)

CASP8AP2

CREM

Description caspase 8 associated protein 2 cAMP responsive element modulator
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Asthma ( 31959851)
  • Estimated glomerular filtration rate in non-diabetics ( 31451708)
  • Major depressive disorder ( 29317602)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 28067908 21102463)
  • Diarrhoea-associated Entamoeba histolytica infection ( 30228239)
  • Inflammatory bowel disease ( 28067908 23128233)
Interacting Genes 19 interacting genes: CALM1 CASP10 CASP8 CREBBP CREM CTBP2 FADD FAS GLUL MX1 NAA10 NR3C2 PML SP100 SREBF2 TCL1A TRAF2 TRIM21 UBE2I 47 interacting genes: AMBRA1 ATF1 ATXN1 BHLHE40 CAMK2D CAMK2G CASP8AP2 CDC34 CDK1 CREB1 CREB3L1 CREBBP CSNK1A1 CSNK2A1 CSNK2A2 CUL2 DNMT3L EMP3 FHL5 GLIS2 GSK3A GSK3B HDAC1 HPCA HPCAL1 KCNIP3 MAPK3 MKNK1 MYOZ3 NCALD NCS1 PIAS3 POU2F1 PRKACA PRKCA RHOXF2 ROR2 RUSC1 SNRPB SNRPC SP100 SPI1 TAF4 TBP UBAP2 UBE2I VENTX
Entrez ID 9994 1390
HPRD ID 06048 00444
Ensembl ID ENSG00000118412 ENSG00000095794
Uniprot IDs Q9UKL3 Q03060
PDB IDs 2LR8 6ANO 6AOZ 6AP0
Enriched GO Terms of Interacting Partners?
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