CREM and CASP8AP2

  • Number of citations of the paper that reports this interaction (PubMedID 21988832)
  • 87
  • Data Source:
  • BioGRID (two hybrid)

CREM

CASP8AP2

Description cAMP responsive element modulator caspase 8 associated protein 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 28067908 21102463)
  • Diarrhoea-associated Entamoeba histolytica infection ( 30228239)
  • Inflammatory bowel disease ( 28067908 23128233)
  • Asthma ( 31959851)
  • Estimated glomerular filtration rate in non-diabetics ( 31451708)
  • Major depressive disorder ( 29317602)
Interacting Genes 47 interacting genes: AMBRA1 ATF1 ATXN1 BHLHE40 CAMK2D CAMK2G CASP8AP2 CDC34 CDK1 CREB1 CREB3L1 CREBBP CSNK1A1 CSNK2A1 CSNK2A2 CUL2 DNMT3L EMP3 FHL5 GLIS2 GSK3A GSK3B HDAC1 HPCA HPCAL1 KCNIP3 MAPK3 MKNK1 MYOZ3 NCALD NCS1 PIAS3 POU2F1 PRKACA PRKCA RHOXF2 ROR2 RUSC1 SNRPB SNRPC SP100 SPI1 TAF4 TBP UBAP2 UBE2I VENTX 19 interacting genes: CALM1 CASP10 CASP8 CREBBP CREM CTBP2 FADD FAS GLUL MX1 NAA10 NR3C2 PML SP100 SREBF2 TCL1A TRAF2 TRIM21 UBE2I
Entrez ID 1390 9994
HPRD ID 00444 06048
Ensembl ID ENSG00000095794 ENSG00000118412
Uniprot IDs Q03060 Q9UKL3
PDB IDs 2LR8 6ANO 6AOZ 6AP0
Enriched GO Terms of Interacting Partners?
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