TOX4 and HIPK3

Number of citations of the paper that reports this interaction (PubMedID 15231748)
99

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TOX4	HIPK3
Description		TOX high mobility group box family member 4	homeodomain interacting protein kinase 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Chromatin Nucleus PTW/PP1 Phosphatase Complex	Nucleus Cytoplasm Cytosol Plasma Membrane Nuclear Body PML Body
	Molecular Function	Protein Binding Chromatin DNA Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Tyrosine Kinase Activity ATP Binding Protein Serine Kinase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Protein Phosphorylation Apoptotic Process MRNA Transcription Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Peptidyl-tyrosine Phosphorylation Negative Regulation Of Apoptotic Process Negative Regulation Of JUN Kinase Activity
Pathways
Drugs			Fostamatinib
Diseases
GWAS			Anger ( 24489884) Obese vs. thin ( 30677029) Sleep (1/3-day periodicity) ( 33075057) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		16 interacting genes: ATXN1 BANP CCBE1 CREB1 EXOSC10 FNDC3B GEMIN6 HIPK3 HSPB1 MYL7 PPP1CA QRICH1 TBX6 WDR82 ZMYND19 ZNF512B	38 interacting genes: AR ARRB2 C1QA CREB1 CREBBP DAXX FADD FAS FLNC GLUL GORASP1 GRB2 HEYL HNRNPA1 HNRNPA2B1 HNRNPH1 LIMD1 LIMK2 LIMS2 MBD1 MTMR4 NR2F2 RGS3 SIAH1 SIAH2 SKIL SNIP1 SRSF1 SRSF5 SUMO1 TGFB1I1 TOX4 TP73 TRA2B UBE2I WT1 ZNF107 ZYX
Entrez ID		9878	10114
HPRD ID		12661	05111
Ensembl ID		ENSG00000092203	ENSG00000110422
Uniprot IDs		O94842	A8KAE4 Q9H422
PDB IDs
Enriched GO Terms of Interacting Partners?
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