TSC22D2 and MTIF2

Number of citations of the paper that reports this interaction (PubMedID 27337956)
22

Data Source:
BioGRID (two hybrid)

		TSC22D2	MTIF2
Description		TSC22 domain family member 2	mitochondrial translational initiation factor 2
Image		No pdb structure
GO Annotations	Cellular Component		Nucleoplasm Mitochondrion
	Molecular Function		RNA Binding Translation Initiation Factor Activity GTPase Activity GTP Binding Translation Factor Activity, RNA Binding Ribosomal Small Subunit Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Response To Osmotic Stress	Regulation Of Translational Initiation Ribosome Disassembly Mitochondrial Translational Initiation
Pathways			Mitochondrial translation initiation
Drugs
Diseases
GWAS		Adiponectin levels ( 22479202) Apolipoprotein A1 levels ( 32203549) Body shape index ( 34021172) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive decline rate in late mild cognitive impairment ( 26252872) Cortical surface area (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Glaucoma ( 31959993) Glaucoma (primary open-angle) ( 33627673 29891935) HDL cholesterol levels ( 32203549) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Intraocular pressure ( 29235454) Macular thickness ( 30535121) Mean platelet volume ( 32888494) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (HMG CoA reductase inhibitors) ( 31015401) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444) Moyamoya disease ( 29273593) PR interval ( 32439900) Pulse pressure ( 27841878) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545) Systolic blood pressure ( 27841878) T wave morphology restitution during recovery from exercise ( 31607149) T wave morphology restitution during recovery from exercise (MTAG) ( 31607149) Triglyceride levels ( 32203549 32154731) Type 2 diabetes ( 30054458 30297969) Waist circumference ( 26785701) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Dementia and core Alzheimer's disease neuropathologic changes ( 25188341)
Interacting Genes		42 interacting genes: ANAPC10 ANKRD36 ARID2 ATP1B1 CCDC141 CCDC144A CLIP1 DNAAF11 ENOPH1 EPCAM F8 FLNB GPBP1 ITGA2 KIAA0586 LOXHD1 LPL MED13 MPDZ MSH3 MTIF2 NGRN OSBPL1A PRMT3 PSMA7 PSMA8 RBL1 REV1 RNF2 SAP18 SCEL SEC31A SNX3 SPEF2 STK39 TMA7 TTN UFM1 WNK3 ZMYM2 ZNF143 ZNF251	4 interacting genes: HSPB1 NAP1L1 NFKBIB TSC22D2
Entrez ID		9819	4528
HPRD ID		11101	04792
Ensembl ID		ENSG00000196428	ENSG00000085760
Uniprot IDs		B4DN36 O75157	P46199 Q6P1N2
PDB IDs			6GAW 6GAZ 6GB2 6RW5
Enriched GO Terms of Interacting Partners?
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