TSC22D2 and CCDC141

Number of citations of the paper that reports this interaction (PubMedID 27337956)
22

Data Source:
BioGRID (two hybrid)

		TSC22D2	CCDC141
Description		TSC22 domain family member 2	coiled-coil domain containing 141
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytoplasm Centrosome Neuron Projection
	Molecular Function		Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Response To Osmotic Stress	Cerebral Cortex Radially Oriented Cell Migration Centrosome Localization
Pathways
Drugs
Diseases
GWAS		Adiponectin levels ( 22479202) Apolipoprotein A1 levels ( 32203549) Body shape index ( 34021172) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive decline rate in late mild cognitive impairment ( 26252872) Cortical surface area (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Glaucoma ( 31959993) Glaucoma (primary open-angle) ( 33627673 29891935) HDL cholesterol levels ( 32203549) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Intraocular pressure ( 29235454) Macular thickness ( 30535121) Mean platelet volume ( 32888494) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (HMG CoA reductase inhibitors) ( 31015401) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444) Moyamoya disease ( 29273593) PR interval ( 32439900) Pulse pressure ( 27841878) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545) Systolic blood pressure ( 27841878) T wave morphology restitution during recovery from exercise ( 31607149) T wave morphology restitution during recovery from exercise (MTAG) ( 31607149) Triglyceride levels ( 32203549 32154731) Type 2 diabetes ( 30054458 30297969) Waist circumference ( 26785701) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Blood pressure measurement (cold pressor test) ( 24165912) Diastolic blood pressure ( 28135244 27841878 30578418) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Heart rate ( 30166351 23583979) Heart rate response to exercise ( 29769521) Heart rate response to recovery post exercise (10 sec) ( 29497042) Heart rate response to recovery post exercise (20 sec) ( 29497042) Left ventricular ejection fraction ( 33495596) Left ventricular end-systolic volume ( 33495596) Left ventricular global circumferential strain ( 33495596) Left ventricular mass ( 33495596) Mucinous adenocarcinoma in colorectal cancer ( 29942513) Number of live births ( 30188897) Number of pregnancies ( 30188897) Objective response to lithium treatment ( 26503763) PR interval ( 32439900) Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale) ( 28525603) Psychosis proneness (revised physical anhedonia scale) ( 28525603) Pulse pressure ( 30578418) QRS duration ( 30012220) QT interval ( 24952745 29874175) Resting heart rate ( 29769521 27798624) Serum polyunsaturated fatty acid concentration x Mediterranean diet adherence interaction in metabolic syndrome ( 31991592) Sick sinus syndrome ( 33580673) Smoking cessation ( 30617275)
Interacting Genes		42 interacting genes: ANAPC10 ANKRD36 ARID2 ATP1B1 CCDC141 CCDC144A CLIP1 DNAAF11 ENOPH1 EPCAM F8 FLNB GPBP1 ITGA2 KIAA0586 LOXHD1 LPL MED13 MPDZ MSH3 MTIF2 NGRN OSBPL1A PRMT3 PSMA7 PSMA8 RBL1 REV1 RNF2 SAP18 SCEL SEC31A SNX3 SPEF2 STK39 TMA7 TTN UFM1 WNK3 ZMYM2 ZNF143 ZNF251	4 interacting genes: DISC1 HOMER3 RRAD TSC22D2
Entrez ID		9819	285025
HPRD ID		11101	08257
Ensembl ID		ENSG00000196428	ENSG00000163492
Uniprot IDs		B4DN36 O75157	B8ZZB3 Q6ZP82
PDB IDs
Enriched GO Terms of Interacting Partners?
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