ARHGAP32 and NPHP1

Number of citations of the paper that reports this interaction (PubMedID 18477472)
5

Data Source:
BioGRID (two hybrid)

		ARHGAP32	NPHP1
Description		Rho GTPase activating protein 32	nephrocystin 1
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GO Annotations	Cellular Component	Golgi Membrane Fibrillar Center Nucleoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Cell Cortex Endosome Membrane Postsynaptic Density Actin Cytoskeleton Dendritic Spine	Cytoplasm Cytosol Cytoskeleton Cell-cell Junction Adherens Junction Bicellular Tight Junction Cilium Membrane Motile Cilium Photoreceptor Connecting Cilium
	Molecular Function	GTPase Activator Activity Protein Binding Phosphatidylinositol Phosphate Binding	Structural Molecule Activity Protein Binding
	Biological Process	Small GTPase Mediated Signal Transduction Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction	Signal Transduction Excretion Visual Behavior Cell Projection Organization Actin Cytoskeleton Organization Spermatid Differentiation Retina Development In Camera-type Eye Protein Localization Involved In Establishment Of Planar Polarity Cell-cell Adhesion Positive Regulation Of Bicellular Tight Junction Assembly
Pathways		RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOQ GTPase cycle RHOG GTPase cycle RHOJ GTPase cycle RAC3 GTPase cycle RHOF GTPase cycle	Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS		Intracranial aneurysm ( 30823506) Iris color (L* coordinate) ( 29109912) Macular thickness ( 30535121) Metabolite levels (5-HIAA) ( 23319000) Refractive error ( 32231278)
Interacting Genes		33 interacting genes: ABI2 ATXN1 BCAR1 CAMK2N2 CDC42 CDH1 CDH2 CRK CRKL CTNNB1 DLG4 DZIP3 FYN GAB1 GAB2 GRAP GRB2 GRIN2A GRIN2B LHX2 MDFI MEGF10 NCK1 NCK2 NPHP1 NTRK1 PIK3R1 PLCG1 RAC1 RHOA SHC3 SRC TLE5	18 interacting genes: ADAM15 ARHGAP32 BCAR1 BCL2L11 COX5B FBXO7 FLNA FLNB FLNC INVS KHDRBS1 NPHP3 NPHP4 PAK2 PTK2B TNK2 TUBB UBQLN4
Entrez ID		9743	4867
HPRD ID		12257	09524
Ensembl ID		ENSG00000134909	ENSG00000144061
Uniprot IDs		A7KAX9 Q86T64	C9JNM7 O15259
PDB IDs		3IUG	1S1N 6O1Q
Enriched GO Terms of Interacting Partners?
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