DCAF1 and IMPDH2

		DCAF1	IMPDH2
Description		DDB1 and CUL4 associated factor 1	inosine monophosphate dehydrogenase 2
Image
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Cul4-RING E3 Ubiquitin Ligase Complex	Extracellular Region Nucleus Cytoplasm Peroxisomal Membrane Cytosol Membrane Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding ATP Binding Estrogen Receptor Binding Protein Serine Kinase Activity Histone Kinase Activity (H2A-T120 Specific)	Nucleotide Binding DNA Binding RNA Binding IMP Dehydrogenase Activity Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Protein Ubiquitination B Cell Differentiation V(D)J Recombination Cell Competition In A Multicellular Organism Histone H2A-T120 Phosphorylation	GMP Biosynthetic Process GTP Biosynthetic Process Circadian Rhythm Lymphocyte Proliferation Retina Development In Camera-type Eye Cellular Response To Interleukin-4
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Neutrophil degranulation Purine ribonucleoside monophosphate biosynthesis Potential therapeutics for SARS
Drugs			NADH Mycophenolate mofetil Ribavirin Mycophenolic acid Mercaptopurine Selenazole-4-carboxyamide-adenine dinucleotide 6-Chloropurine Riboside, 5'-Monophosphate Inosinic Acid VX-148
Diseases
GWAS		Asthma ( 32296059)	Blood protein levels ( 28240269) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		22 interacting genes: ATM ATR CCP110 EXO1 FOXM1 H3-3A H3-4 H3C1 HLTF IMPDH2 KATNA1 NF2 PRKDC PWP1 PYGO2 RAG1 RBX1 SAMHD1 TET2 TP53 UBE2D2 UBE2D3	32 interacting genes: AGR2 AKT1 ALS2 AMT APIP APPL1 ATXN2 ATXN7 C1S CEACAM5 CLK1 CPLANE2 DCAF1 DNASE1L3 FBXL7 FXR1 FXR2 IL1F10 KLF7 OGT PIAS4 POU6F2 PRMT1 PXMP2 PXN RAD54L2 RBM15B STAT3 SUMO2 SUMO4 TRAF2 UBQLN4
Entrez ID		9730	3615
HPRD ID		11674	00895
Ensembl ID		ENSG00000145041	ENSG00000178035
Uniprot IDs		Q9Y4B6	A0A384N6C2 P12268
PDB IDs		3WA0 4CC9 4P7I 4PXW 4Z8L 5AJA 5JK7 6N45	1B3O 1NF7 1NFB 6I0M 6I0O 6U8E 6U8N 6U8R 6U8S 6U9O 6UA2 6UA4 6UA5 6UAJ 6UC2 6UDO 6UDP 6UDQ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?