PHF14 and TMEM106B

		PHF14	TMEM106B
Description		PHD finger protein 14	transmembrane protein 106B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	MOZ/MORF Histone Acetyltransferase Complex	Lysosome Lysosomal Membrane Endosome Integral Component Of Membrane Late Endosome Membrane
	Molecular Function	Protein Binding Histone Binding Metal Ion Binding	Molecular_function Protein Binding ATPase Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Histone H3-K14 Acetylation	Lysosome Organization Lysosomal Transport Lysosomal Lumen Acidification Lysosome Localization Dendrite Morphogenesis Positive Regulation Of Hydrolase Activity Positive Regulation Of Dendrite Development Lysosomal Protein Catabolic Process Regulation Of Lysosome Organization
Pathways
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Self-reported childhood asthma in adult smokers ( 30373671)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors) ( 23648065) Alzheimer's disease (APOE e4 interaction) ( 25778476) Apolipoprotein A1 levels ( 32203549) Blood protein levels ( 30072576) Cigarettes smoked per day in Schizophrenia ( 33691233) Coronary artery disease ( 29212778 33020668) Crohn's disease ( 32581322) Depression ( 33859377 29700475) Differential aging (frontal cortex) ( 28330615) Differential aging in older adults (frontal cortex) ( 28330615) Experiencing mood swings ( 29500382) Frontotemporal dementia ( 29724592) Frontotemporal dementia with GRN mutation ( 29724592) General factor of neuroticism ( 30867560) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) Idiopathic dilated cardiomyopathy ( 29495422) Lifetime anxiety disorder ( 31748690) Liver enzyme levels (alkaline phosphatase) ( 33972514) Myocardial infarction ( 33532862) Neurociticism ( 29500382) Neuroticism ( 29255261) Plasma kynurenine levels in major depressive disorder ( 29317604) Residual cognition ( 28441426) Response to amphetamines ( 22952603) Response to taxane treatment (placlitaxel) ( 23006423) Serum alkaline phosphatase levels ( 33547301) Tourette syndrome ( 22889924) Triglycerides ( 30275531)
Interacting Genes		2 interacting genes: PCBD2 TMEM106B	2 interacting genes: PHF14 TMEM106C
Entrez ID		9678	54664
HPRD ID		17845	07745
Ensembl ID		ENSG00000106443	ENSG00000106460
Uniprot IDs		B4DG57 O94880	A0A024R9Z1 Q9NUM4
PDB IDs
Enriched GO Terms of Interacting Partners?
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