TMEM106B and PHF14

		TMEM106B	PHF14
Description		transmembrane protein 106B	PHD finger protein 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Integral Component Of Membrane Late Endosome Membrane	MOZ/MORF Histone Acetyltransferase Complex
	Molecular Function	Molecular_function Protein Binding ATPase Binding	Protein Binding Histone Binding Metal Ion Binding
	Biological Process	Lysosome Organization Lysosomal Transport Lysosomal Lumen Acidification Lysosome Localization Dendrite Morphogenesis Positive Regulation Of Hydrolase Activity Positive Regulation Of Dendrite Development Lysosomal Protein Catabolic Process Regulation Of Lysosome Organization	Regulation Of Transcription By RNA Polymerase II Histone H3-K14 Acetylation
Pathways
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors) ( 23648065) Alzheimer's disease (APOE e4 interaction) ( 25778476) Apolipoprotein A1 levels ( 32203549) Blood protein levels ( 30072576) Cigarettes smoked per day in Schizophrenia ( 33691233) Coronary artery disease ( 29212778 33020668) Crohn's disease ( 32581322) Depression ( 33859377 29700475) Differential aging (frontal cortex) ( 28330615) Differential aging in older adults (frontal cortex) ( 28330615) Experiencing mood swings ( 29500382) Frontotemporal dementia ( 29724592) Frontotemporal dementia with GRN mutation ( 29724592) General factor of neuroticism ( 30867560) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) Idiopathic dilated cardiomyopathy ( 29495422) Lifetime anxiety disorder ( 31748690) Liver enzyme levels (alkaline phosphatase) ( 33972514) Myocardial infarction ( 33532862) Neurociticism ( 29500382) Neuroticism ( 29255261) Plasma kynurenine levels in major depressive disorder ( 29317604) Residual cognition ( 28441426) Response to amphetamines ( 22952603) Response to taxane treatment (placlitaxel) ( 23006423) Serum alkaline phosphatase levels ( 33547301) Tourette syndrome ( 22889924) Triglycerides ( 30275531)	Metabolite levels ( 23823483) Self-reported childhood asthma in adult smokers ( 30373671)
Interacting Genes		2 interacting genes: PHF14 TMEM106C	2 interacting genes: PCBD2 TMEM106B
Entrez ID		54664	9678
HPRD ID		07745	17845
Ensembl ID		ENSG00000106460	ENSG00000106443
Uniprot IDs		A0A024R9Z1 Q9NUM4	B4DG57 O94880
PDB IDs
Enriched GO Terms of Interacting Partners?
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