TRAF4 and EYA2

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

TRAF4

EYA2

Description TNF receptor associated factor 4 EYA transcriptional coactivator and phosphatase 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359)
  • Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359)
  • Allergic rhinitis ( 31361310)
  • Asthma ( 32296059)
  • Body fat percentage and triglycerides (pairwise) ( 33619380)
  • Body shape index ( 34021172)
  • Brain volume in infants (intracranial brain volume) ( 28763065)
  • Coffee consumption ( 31046077)
  • Fasting insulin ( 34059833)
  • FEV1 ( 30804560)
  • Glaucoma (primary open-angle) ( 33627673)
  • Heel bone mineral density ( 30598549 28869591)
  • High light scatter reticulocyte count ( 32888494)
  • High light scatter reticulocyte percentage of red cells ( 32888494)
  • Hip circumference adjusted for BMI ( 34021172)
  • Hip index ( 34021172)
  • Liver enzyme levels (alanine transaminase) ( 33972514)
  • Lung function (FVC) ( 30061609 30804560)
  • Non-del(5q) myelodysplastic syndromes ( 31738830)
  • Peak expiratory flow ( 30804560)
  • Reticulocyte count ( 32888494)
  • Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
  • Triglyceride levels ( 32203549 32154731)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Type 2 diabetes ( 30054458 30297969)
  • Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
  • Waist circumference adjusted for body mass index ( 34021172)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172 26426971)
  • Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
  • Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
Interacting Genes 133 interacting genes: ABI3 ALKBH4 ATOX1 BACH2 BAHD1 BANP BCKDK BCL6B BEGAIN BEX3 BYSL C19orf54 CALCOCO2 CBL CBLC CCHCR1 CENPE CEP85 CHEK1 CHUK DISC1 DNM2 DPEP2NB DTX3 EXOC7 EYA2 EZHIP FAM214B FAM90A1 FAT1 FBXL18 FRS3 FTH1 GOLGA2 GOLGA6A GOLGA6L9 GORASP1 GORASP2 GPRASP1 HEY2 HGS HMG20A HOMEZ HOXA1 HOXB5 IRAK1 ISYNA1 KANK2 KANSL1 KDM1A KRT31 KRT36 KRT40 LENG8 LNX1 LTBR MAGEC2 MAGED1 MAP3K4 MRPL28 NCF1 NGFR NOS1AP NPAS2 NTRK1 NUDT16L1 OGT PCSK5 PDE4DIP PHLDA1 PICK1 PKD1P1 PLAGL2 PLEKHA7 PLSCR1 POLR2J POLR2J3 PSMC3 QARS1 RAD54L2 RBPMS REXO1L6P RNF114 RNF144B RNF4 RPS6KB1 SF3B4 SIGLEC7 SLC9A3R2 SMURF1 SMURF2 SNRPB SORBS2 SPDL1 SUMO1 TARBP2 TAX1BP1 TBC1D7 TBC1D8 TFAP4 TGFB1I1 TICAM1 TNFRSF4 TP53BP2 TRAF6 TRIM27 TRIM37 TSGA10IP TYK2 UBE2D1 UBE2I UBL4A UBL4B USP7 VPS52 WBP11 WWP1 WWP2 ZBTB16 ZBTB26 ZC3H12C ZMYM5 ZNF177 ZNF275 ZNF3 ZNF512B ZNF559-ZNF177 ZNF581 ZNF620 ZNF688 ZNF784 ZNF835 ZRANB1 36 interacting genes: AATK BAG3 CATSPER1 CDK18 DMRTB1 DTX2 DUSP21 ENKD1 FAM214B GNAI2 GNAZ HGS IQUB LGALS4 LOX MED25 PATZ1 PAX9 PIN1 POGZ RBPMS RFX2 ROR2 SIX1 SIX4 SNRPC SPG21 SUOX TEKT4 TEKT5 TFG TLE5 TRAF4 TRAPPC6A TSSK3 VPS37C
Entrez ID 9618 2139
HPRD ID 03915 09041
Ensembl ID ENSG00000076604 ENSG00000064655
Uniprot IDs A0A024QZ19 A0A024QZ59 Q9BUZ4 E7ETN2 O00167
PDB IDs 2EOD 2YUC 3ZJB 4K8U 4M4E 5YC1 3GEB 3HB0 3HB1 4EGC 5ZMA
Enriched GO Terms of Interacting Partners?
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