EYA2 and ENKD1

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

EYA2

ENKD1

Description EYA transcriptional coactivator and phosphatase 2 enkurin domain containing 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359)
  • Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359)
  • Allergic rhinitis ( 31361310)
  • Asthma ( 32296059)
  • Body fat percentage and triglycerides (pairwise) ( 33619380)
  • Body shape index ( 34021172)
  • Brain volume in infants (intracranial brain volume) ( 28763065)
  • Coffee consumption ( 31046077)
  • Fasting insulin ( 34059833)
  • FEV1 ( 30804560)
  • Glaucoma (primary open-angle) ( 33627673)
  • Heel bone mineral density ( 30598549 28869591)
  • High light scatter reticulocyte count ( 32888494)
  • High light scatter reticulocyte percentage of red cells ( 32888494)
  • Hip circumference adjusted for BMI ( 34021172)
  • Hip index ( 34021172)
  • Liver enzyme levels (alanine transaminase) ( 33972514)
  • Lung function (FVC) ( 30061609 30804560)
  • Non-del(5q) myelodysplastic syndromes ( 31738830)
  • Peak expiratory flow ( 30804560)
  • Reticulocyte count ( 32888494)
  • Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
  • Triglyceride levels ( 32203549 32154731)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Type 2 diabetes ( 30054458 30297969)
  • Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
  • Waist circumference adjusted for body mass index ( 34021172)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172 26426971)
  • Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
  • Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
Interacting Genes 36 interacting genes: AATK BAG3 CATSPER1 CDK18 DMRTB1 DTX2 DUSP21 ENKD1 FAM214B GNAI2 GNAZ HGS IQUB LGALS4 LOX MED25 PATZ1 PAX9 PIN1 POGZ RBPMS RFX2 ROR2 SIX1 SIX4 SNRPC SPG21 SUOX TEKT4 TEKT5 TFG TLE5 TRAF4 TRAPPC6A TSSK3 VPS37C 207 interacting genes: ABI1 ABI2 ACOT7 AKAP8L ANKRD23 ANKRD49 APP ARMC5 ASB3 AVPI1 BANP BCAS2 BCAS4 BCAT1 BEGAIN BEX3 BHLHB9 BLZF1 BRAT1 C18orf54 C19orf54 C1orf105 CALCOCO1 CALCOCO2 CBY1 CBY2 CCDC102B CCDC13 CCDC136 CCDC28B CCDC85B CDCA4 CDPF1 CDR2 CDSN CEP55 CEP70 CHCHD3 CHRDL2 COA7 CTBP2 CYSRT1 DGCR6 DVL2 DVL3 DYDC1 ECM1 EFHC2 EIF4G1 EYA2 EZHIP FAM102A FAM228A FAM90A1 FCHSD2 FKBP6 FOS FOSB FSD2 GADD45G GADD45GIP1 GET4 GFAP GIGYF1 GOLGA2 GOLGA6A GOLGA6L9 GRHL3 GRIPAP1 HMBOX1 HNRNPH1 HOMEZ HOOK2 HOXA1 HSF2BP HSPB2 HSPB2-C11orf52 ID2 IGF1 IGFBP6 IKBKG IKZF3 JAKMIP1 KIFC3 KLHL20 KLHL26 KRT14 KRT15 KRT31 KRT35 KRT40 KRTAP10-5 KRTAP10-8 KRTAP11-1 KRTAP12-1 KRTAP13-2 KRTAP19-1 KRTAP19-5 KRTAP19-6 KRTAP4-11 KRTAP5-9 KRTAP6-2 LDOC1 LHX3 LIN7B LMO2 LRRC61 LZTS1 MAPK9 MATN4 MDFI MEIS3 MESD METTL27 MID2 MIF4GD MIPOL1 MISP MKRN3 MLH1 MORN3 MORN5 MRNIP MRPL28 MRPL38 MTUS2 MYF5 MYOZ3 N4BP3 NAB2 NBPF22P NBPF6 NCKIPSD NDUFB7 NEFL NFKBIA NHLRC4 NUTM1 OOEP PAK5 PDLIM7 PDZD4 PHC2 PIBF1 PICK1 PIK3R3 PKNOX2 PLSCR1 PNMA1 PNMA2 POLR3C PPP1CC PPP2R3C PRDM14 PRDM6 RAD54B RBCK1 RBM11 RBPMS RCN1 RUBCN RUNDC3A SLC15A2 SNRNP48 SORBS3 SPAG5 SPDEF SPSB3 SRGAP3 SSC4D STAC3 STXBP4 TENT5B TNNI1 TNS2 TOX2 TRAF1 TRAF2 TRAK1 TRGV7 TRIM23 TRIM27 TRIM35 TRIM54 TSC1 TSC22D4 TSEN15 UBXN11 USH1C USH1G USHBP1 USP20 VBP1 VPS37B VWC2 WDR62 WWOX YWHAE ZBTB14 ZC2HC1C ZFP90 ZNF143 ZNF426 ZNF511 ZNF581 ZNF76 ZRANB1
Entrez ID 2139 84080
HPRD ID 09041 13151
Ensembl ID ENSG00000064655 ENSG00000124074
Uniprot IDs E7ETN2 O00167 Q9H0I2
PDB IDs 3GEB 3HB0 3HB1 4EGC 5ZMA
Enriched GO Terms of Interacting Partners?
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