ORMDL1 and TMEM143

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

		ORMDL1	TMEM143
Description		ORMDL sphingolipid biosynthesis regulator 1	transmembrane protein 143
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane SPOTS Complex	Mitochondrion Integral Component Of Membrane
	Molecular Function	Protein Binding	Molecular_function Protein Binding
	Biological Process	Ceramide Metabolic Process Cellular Sphingolipid Homeostasis Negative Regulation Of Ceramide Biosynthetic Process	Biological_process
Pathways		Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS		Bilirubin levels ( 20639394) Ferritin levels ( 25162662)
Interacting Genes		37 interacting genes: APP AQP6 ARL13B ASGR2 COQ9 CPLX4 CREB3 CREB3L1 EBAG9 EBP EHHADH ERGIC3 GPR152 HSD17B11 KCNK4 LMNA LNX1 MFSD14B PCNX2 PGRMC2 REEP4 SAR1A SCN3B SLC10A1 SLC10A6 SLC18A1 SLC30A8 SLC35C2 STOM TLCD4 TMEM143 TMEM14B TMEM35A TMEM52B VMA21 ZDHHC15 ZFYVE27	15 interacting genes: ABHD16A AQP6 CSGALNACT2 DGAT2L6 DHRSX DYNLT1 LIME1 LSMEM2 NAT8 ORMDL1 REEP6 SFT2D2 SLC10A6 TMEM120B YIPF2
Entrez ID		94101	55260
HPRD ID		15092	08556
Ensembl ID		ENSG00000128699	ENSG00000161558
Uniprot IDs		Q9P0S3	B4DMT0 B4DPF8 Q96AN5
PDB IDs
Enriched GO Terms of Interacting Partners?
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