ZFYVE9 and ATP6V0B

		ZFYVE9	ATP6V0B
Description		zinc finger FYVE-type containing 9	ATPase H+ transporting V0 subunit b
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GO Annotations	Cellular Component	Early Endosome Cytosol Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle	Lysosomal Membrane Endosome Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain
	Molecular Function	Protein Binding 1-phosphatidylinositol Binding Protein Domain Specific Binding Metal Ion Binding	Transporter Activity Protein Binding Proton Transmembrane Transporter Activity
	Biological Process	Endocytosis Transforming Growth Factor Beta Receptor Signaling Pathway Endosomal Transport	Regulation Of Macroautophagy Proton Transmembrane Transport
Pathways			ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs			Tiludronic acid
Diseases
GWAS		Hip circumference adjusted for BMI ( 34021172)	Autism spectrum disorder or schizophrenia ( 28540026)
Interacting Genes		40 interacting genes: ANKLE2 ATP6V0B BAG6 BMP4 CHD6 CLTC CTNNB1 DAZAP2 EIF4G1 ERBIN ETS2 FHL2 JUP LRP12 NIT1 NRDC NUP155 PML PPP1CA PPP1CB PPP1CC PPP2R1A RBBP6 RHOT2 RNF11 RNPEP SCYL2 SMAD2 SMAD3 SPART ST7 SUMF2 SUPT5H SVEP1 TENT5A TGFBR1 TGFBR2 UBC UBXN11 ZMYND8	34 interacting genes: ADGRG3 ADRB2 APOD BPI CCL19 COL4A5 DAPK2 EMP1 FAM210B FAS GJA8 GPR42 GPR61 INSIG2 IRAK3 KLRC1 MFF MIP MS4A3 MTNR1B NRM RPS26P15 SLC10A1 SLC2A5 SNTA1 SPACA1 STOM TM4SF19 TMEM242 TTC39A VMA21 YWHAE YWHAG ZFYVE9
Entrez ID		9372	533
HPRD ID		04782	04759
Ensembl ID		ENSG00000157077	ENSG00000117410
Uniprot IDs		O95405	E9PNL3 Q99437
PDB IDs		1DEV 1MK2 4BKW 5MJY	6WLW 6WM2 6WM3 6WM4
Enriched GO Terms of Interacting Partners?
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