ATP6V0B and SPACA1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ATP6V0B	SPACA1
Description		ATPase H+ transporting V0 subunit b	sperm acrosome associated 1
Image			No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Endosome Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain	Inner Acrosomal Membrane Acrosomal Membrane Integral Component Of Membrane
	Molecular Function	Transporter Activity Protein Binding Proton Transmembrane Transporter Activity	Protein Binding
	Biological Process	Regulation Of Macroautophagy Proton Transmembrane Transport	Acrosome Assembly
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs		Tiludronic acid
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026)	Echocardiographic traits ( 17903301) Left superior temporal gyrus thickness (schizophrenia interaction) ( 26249676) Triglyceride levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder ( 33824429)
Interacting Genes		34 interacting genes: ADGRG3 ADRB2 APOD BPI CCL19 COL4A5 DAPK2 EMP1 FAM210B FAS GJA8 GPR42 GPR61 INSIG2 IRAK3 KLRC1 MFF MIP MS4A3 MTNR1B NRM RPS26P15 SLC10A1 SLC2A5 SNTA1 SPACA1 STOM TM4SF19 TMEM242 TTC39A VMA21 YWHAE YWHAG ZFYVE9	25 interacting genes: AGPAT4 ATP6V0B ATP6V0C BNIP3 CACNG7 CD72 CLDN19 CTXN3 EMP1 EMP3 GIMAP5 LSMEM2 NRSN1 NSG1 PLN PMP22 RPRM SERP2 SERTM1 SGCG SMAGP SMIM3 THSD7B TMEM140 TMEM47
Entrez ID		533	81833
HPRD ID		04759	15419
Ensembl ID		ENSG00000117410	ENSG00000118434
Uniprot IDs		E9PNL3 Q99437	Q9HBV2
PDB IDs		6WLW 6WM2 6WM3 6WM4
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?