SYCE1 and PSTPIP1

Number of citations of the paper that reports this interaction (PubMedID 26871637)
172

Data Source:
BioGRID (two hybrid)

		SYCE1	PSTPIP1
Description		synaptonemal complex central element protein 1	proline-serine-threonine phosphatase interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Central Element Nucleoplasm Chromosome Cytosol Intracellular Membrane-bounded Organelle	Uropod Cytoplasm Cytosol Actin Filament Plasma Membrane Membrane Lamellipodium Cleavage Furrow Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding Actin Filament Binding
	Biological Process	Synaptonemal Complex Assembly Cell Division	Endocytosis Inflammatory Response Cell Adhesion Signal Transduction Actin Filament Polymerization Innate Immune Response
Pathways		Meiotic synapsis	The NLRP3 inflammasome Purinergic signaling in leishmaniasis infection
Drugs
Diseases
GWAS			Hip circumference adjusted for BMI ( 34021172) Neurofibrillary tangles ( 31497858) Neutrophil count ( 32888494) White blood cell count ( 32888494)
Interacting Genes		49 interacting genes: ALOX5 ARNT2 BEX2 BFSP2 CBY2 CCDC102B CCHCR1 CFAP100 CINP CNN1 CYTH3 EDRF1 EXOC8 FAM161A FAM161B HAUS1 HMG20B HOOK1 HSPB1 HSPB7 IQUB KAT5 KIFC3 KRT18 LMNA MBD3 MPV17 MRFAP1L1 NME7 PSTPIP1 RALBP1 RBCK1 RUNX1T1 SCNM1 SKA1 SMARCE1 SPATC1L SSX2 STX19 TFIP11 TPM1 TPM3 TRAF1 TRIM41 TSG101 TXN2 VPS25 WASHC3 ZNF124	65 interacting genes: ABL1 AXIN1 BUB3 CCDC172 CD2 CD2AP CHD4 CWF19L2 DHX40 DNM2 EHHADH EXOC5 FAM90A1 FASLG FBXL18 HAPLN2 HHEX HMG20A HSF2BP IL16 KANK2 KHDRBS1 LIN37 LSM4 MCRS1 MEFV MFGE8 MOS MVP NAV2 NCBP1 PCDHB14 PNKP PRPF31 PRR35 PTPN12 PTPN18 RINT1 RNPS1 RPL9 RTP5 RXRB SCNM1 SDCBP SH2D4A SHBG SMARCD1 SPG7 SYCE1 TFIP11 TPH1 TRAF3IP3 TSGA10IP TTC1 TULP3 UBE2W WAS WASF1 WASF2 WASL ZC2HC1C ZNF175 ZNF408 ZNF580 ZNF688
Entrez ID		93426	9051
HPRD ID		12598	05891
Ensembl ID		ENSG00000171772	ENSG00000140368
Uniprot IDs		A0A0B4J1R9 Q8N0S2	A0A0S2Z5P3 O43586
PDB IDs			2DIL
Enriched GO Terms of Interacting Partners?
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